|
| Status |
Public on Mar 04, 2024 |
| Title |
O-GlcNAcylation of CTCF regulates 3D chromatin structure [RNA-seq] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The goal of this study is to test whether the O-GlcNAcylation of CTCF plays a role in regulating chromatin structure.
|
| |
|
| Overall design |
We used HiC to test the changes of 3D chromtin sttucture after muating the O-GlcNAcylation of CTCF. ChIP-seq was used to test the function of O-GlcNAcylation in CTCF chromatin binding. RNA-seq was perforemed to test the changes of genes expression in same condition. ATAC-seq was used to test the change of the chromatin accessibility.
|
| |
|
| Contributor(s) |
Ding J, Tang X, Zeng P |
| Citation(s) |
38561336 |
| BioProject |
PRJNA1070848 |
| |
| Submission date |
Feb 15, 2024 |
| Last update date |
Apr 17, 2024 |
| Contact name |
Zeng Pengguihang |
| E-mail(s) |
zengpgh@mail3.sysu.edu.cn
|
| Organization name |
Sun Yat-Sen University
|
| Street address |
No.74, Zhongshan 2nd Road, Guangzhou, Guangdong
|
| City |
Guanghzou |
| ZIP/Postal code |
510080 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (4)
|
|
| This SubSeries is part of SuperSeries: |
| GSE255897 |
O-GlcNAcylation of CTCF regulates 3D chromatin structure |
|
Less...
More...