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| Status |
Public on Dec 18, 2011 |
| Title |
Expression data from DMSO and SP600125 treated neurons |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Expression profiling of from DMSO and SP600125 treated glutamatergic neurons reveals JNK target genes that are transcriptionally regulated by JNK signaling.
SP600125 is a known JNK signaling inhibitor and therefore, we used this to test whether the expression of JNK bound genes is affected upon inhibition of JNK kinase activity.
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| Overall design |
Gene expression in the SP600125 treated neurons was compared to the DMSO treated neurons. a to e suffixes indicate biological replicates. Batch indicates different batches of the drug SP600125.
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| Contributor(s) |
Tiwari V, Stadler MB, Wirbelauer C, Paro R, Schübeler D, Beisel C |
| Citation(s) |
22179133, 22474351 |
| |
| Submission date |
Nov 22, 2010 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Dirk Schuebeler |
| Organization name |
Friedrich Miescher Institute for Biomedical Research
|
| Street address |
Maulbeerstrasse 66
|
| City |
Basel |
| ZIP/Postal code |
4058 |
| Country |
Switzerland |
| |
|
| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (10)
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| This SubSeries is part of SuperSeries: |
| GSE25533 |
A chromatin-modifying function of JNK during embryonic stem cell differentiation |
|
| Relations |
| BioProject |
PRJNA142431 |
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