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| Status |
Public on Aug 26, 2024 |
| Title |
Inhibition of Renin Expression Is Regulated by an Epigenetic Switch From an Active to a Poised State |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
Expression profiling by high throughput sequencing
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| Summary |
This SuperSeries is composed of the SubSeries listed below.
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| Overall design |
Refer to individual Series
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| Citation(s) |
38989586 |
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| Submission date |
Feb 02, 2024 |
| Last update date |
Aug 27, 2024 |
| Contact name |
Jason Paul Smith |
| E-mail(s) |
jasonsmith@virginia.edu
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| Phone |
9193455043
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| Organization name |
University of Virginia
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| Department |
Pediatrics
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| Lab |
Gomez Sequeira-Lopez
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| Street address |
409 Lane Rd
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| City |
Charlottesville |
| State/province |
VA |
| ZIP/Postal code |
22903 |
| Country |
USA |
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| Platforms (2) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (34)
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| GSM8060478 |
As4.1 cells treated with 10 μM A-485, replicate 1 |
| GSM8060479 |
As4.1 cells treated with 10 μM A-485, replicate 2 |
| GSM8060480 |
As4.1 cells treated with 10 μM H89, replicate 1 |
| GSM8060481 |
As4.1 cells treated with 10 μM H89, replicate 2 |
| GSM8060482 |
As4.1 cells treated with DMSO, replicate 1 |
| GSM8060483 |
As4.1 cells treated with DMSO, replicate 2 |
| GSM8060484 |
As4.1 cells treated with DMSO, replicate 3 |
| GSM8060485 |
As4.1 cells treated with DMSO, replicate 4 |
| GSM8060486 |
As4.1 cells treated with 1 μM JQ1, replicate 1 |
| GSM8060487 |
As4.1 cells treated with 1 μM JQ1, replicate 2 |
| GSM8060488 |
As4.1 cells, DMSO, H3K27ac, rep1 |
| GSM8060489 |
As4.1 cells, DMSO, H3K27ac, rep2 |
| GSM8060490 |
As4.1 cells, H89, H3K27ac, rep1 |
| GSM8060491 |
As4.1 cells, H89, H3K27ac, rep2 |
| GSM8060492 |
As4.1 cells, DMSO, p300, rep1 |
| GSM8060493 |
As4.1 cells, DMSO, p300, rep2 |
| GSM8060494 |
As4.1 cells, H89, p300, rep1 |
| GSM8060495 |
As4.1 cells, H89, p300, rep2 |
| GSM8060496 |
As4.1 cells, Input |
| GSM8060603 |
As4.1 cells, H3K4me1, rep1 |
| GSM8060604 |
As4.1 cells, H3K4me1, rep2 |
| GSM8060605 |
As4.1 cells, H3K4me3, rep1 |
| GSM8060606 |
As4.1 cells, H3K4me3, rep2 |
| GSM8060607 |
As4.1 cells, H2BK5ac, rep1 |
| GSM8060608 |
As4.1 cells, H2BK5ac, rep2 |
| GSM8060609 |
As4.1 cells, H4K16ac, rep1 |
| GSM8060610 |
As4.1 cells, H4K16ac, rep2 |
| GSM8060611 |
As4.1 cells, H4K5ac, rep1 |
| GSM8060612 |
As4.1 cells, H4K5ac, rep2 |
| GSM8060613 |
As4.1 cells, H3K27ac, rep1 |
| GSM8060614 |
As4.1 cells, H3K27ac, rep2 |
| GSM8060615 |
As4.1 cells, IgG |
| GSM8060616 |
As4.1 cells treated with 10 μM H89 |
| GSM8060617 |
As4.1 cells treated with DMSO |
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| This SuperSeries is composed of the following SubSeries:
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| GSE254940 |
Renin Regulatory Pathway Inhibition Epigenetically Silences *Ren1* (ATAC-Seq) |
| GSE254941 |
Renin Regulatory Pathway Inhibition Epigenetically Silences *Ren1* (ChIP-Seq) |
| GSE254943 |
Renin Regulatory Pathway Inhibition Epigenetically Silences *Ren1* (CUTnTag) |
| GSE254944 |
Renin Regulatory Pathway Inhibition Epigenetically Silences *Ren1* (scRNA-Seq) |
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| Relations |
| BioProject |
PRJNA1072672 |
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