|
| Status |
Public on May 01, 2024 |
| Title |
SNP genotyping array of human naive pluripotent stem cells II |
| Organism |
Homo sapiens |
| Experiment type |
SNP genotyping by SNP array
Genome variation profiling by SNP array
|
| Summary |
Human pluripotent stem cells have two major pluripotent states, primed and naive, and the heterogeneity among cell lines in each pluripotent state remains a major unresolved problem. We showed that the overexpression of H1FOO-DD, which has a short expression period by fusing the destabilized domain to the maternal-specific linker histone H1FOO, together with OCT4, SOX2, KLF4 and LMYC in human somatic cells improves the quality of reprogramming to primed and naive pluripotency.
|
| |
|
| Overall design |
Genomic DNA from the 30 samples were hybridized onto the Infinium OmniExpress24 v1.4 DNA Analysis Kit (Illumina), and intensities were scanned by iScan (Illumina) following the manufacturer’s protocol.
|
| |
|
| Contributor(s) |
Kunitomi A, Nomura M |
| Citation(s) |
38701780 |
| |
| Submission date |
Jan 22, 2024 |
| Last update date |
Jun 06, 2024 |
| Contact name |
Akira Kunitomi |
| E-mail(s) |
akira.kunitomi@gladstone.ucsf.edu
|
| Organization name |
The J. David Gladstone Institutes
|
| Street address |
1650 Owens Street
|
| City |
San Francisco |
| State/province |
CA |
| ZIP/Postal code |
94158 |
| Country |
USA |
| |
|
| Platforms (1) |
|
| Samples (30)
|
|
| This SubSeries is part of SuperSeries: |
| GSE224850 |
H1FOO-DD promotes efficiency and uniformity in reprogramming to naive pluripotency |
|
| Relations |
| BioProject |
PRJNA1067680 |
Less...
More...