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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Jan 25, 2024 |
| Title |
Med12 cooperates with multiple differentiation signals to facilitate efficient lineage transitions in embryonic stem cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
This SuperSeries is composed of the SubSeries listed below.
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| Overall design |
Refer to individual Series
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| Web link |
https://doi.org/10.1101/2024.01.22.576603
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| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Jan 18, 2024 |
| Last update date |
Mar 12, 2025 |
| Contact name |
Max Fernkorn |
| E-mail(s) |
m.fernkorn@lacdr.leidenuniv.nl
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| Organization name |
University Leiden
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| Department |
Leiden Academic Centre for Drug Research (LACDR)
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| Lab |
Drukker
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| Street address |
Einsteinweg 55
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| City |
Leiden |
| ZIP/Postal code |
2333 CC |
| Country |
Germany |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (38)
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| GSM8024019 |
Fgf4 Med12 double mutant mESCs, unstimulated, clone 1, rep1 |
| GSM8024020 |
Fgf4 Med12 double mutant mESCs, unstimulated, clone 1, rep2 |
| GSM8024021 |
Fgf4 Med12 double mutant mESCs, unstimulated, clone 1, rep3 |
| GSM8024022 |
Fgf4 Med12 double mutant mESCs, stimulated with 40 ng/ml FGF4 for 6h, clone 1, rep1 |
| GSM8024023 |
Fgf4 Med12 double mutant mESCs, stimulated with 40 ng/ml FGF4 for 6h, clone 1, rep2 |
| GSM8024024 |
Fgf4 Med12 double mutant mESCs, stimulated with 40 ng/ml FGF4 for 6h, clone 1, rep3 |
| GSM8024025 |
Fgf4 Med12 double mutant mESCs, unstimulated, clone 2, rep1 |
| GSM8024026 |
Fgf4 Med12 double mutant mESCs, stimulated with 40 ng/ml FGF4 for 6h, clone 2, rep1 |
| GSM8024027 |
Fgf4 Med12 double mutant mESCs, unstimulated, clone 3, rep1 |
| GSM8024028 |
Fgf4 Med12 double mutant mESCs, stimulated with 40 ng/ml FGF4 for 6h, clone 3, rep1 |
| GSM8024029 |
Fgf4 mutant mESCs, unstimulated, clone 1, rep1 |
| GSM8024030 |
Fgf4 mutant mESCs, unstimulated, clone 1, rep2 |
| GSM8024031 |
Fgf4 mutant mESCs, unstimulated, clone 1, rep3 |
| GSM8024032 |
Fgf4 mutant mESCs, stimulated with 40 ng/ml FGF4 for 6h, clone 1, rep1 |
| GSM8024033 |
Fgf4 mutant mESCs, stimulated with 40 ng/ml FGF4 for 6h, clone 1, rep2 |
| GSM8024034 |
Fgf4 mutant mESCs, stimulated with 40 ng/ml FGF4 for 6h, clone 1, rep3 |
| GSM8024035 |
mESCs, unstimulated |
| GSM8024036 |
mESCs, stimulated, 6h 0.625 ng/ml FGF4 |
| GSM8024037 |
mESCs, stimulated, 6h 1.25 ng/ml FGF4 |
| GSM8024038 |
mESCs, stimulated, 6h 2.5 ng/ml FGF4 |
| GSM8024039 |
mESCs, stimulated, 6h 5 ng/ml FGF4 |
| GSM8024040 |
mESCs, stimulated, 6h 10 ng/ml FGF4 |
| GSM8024041 |
mESCs, stimulated, 6h 20 ng/ml FGF4 |
| GSM8024042 |
mESCs, stimulated, 6h 40 ng/ml FGF4 |
| GSM8024043 |
wt, 2i, rep1 |
| GSM8024044 |
wt, 2i, rep2 |
| GSM8024045 |
wt, 2i, rep3 |
| GSM8024046 |
wt, N2B27, rep1 |
| GSM8024047 |
wt, N2B27, rep2 |
| GSM8024048 |
wt, N2B27, rep3 |
| GSM8024049 |
Med12 mutant, 2i, rep1 |
| GSM8024050 |
Med12 mutant, 2i, rep2 |
| GSM8024051 |
Med12 mutant, 2i, rep3 |
| GSM8024052 |
Med12 mutant, N2B27, rep1 |
| GSM8024053 |
Med12 mutant, N2B27, rep2 |
| GSM8024054 |
Med12 mutant, N2B27, rep3 |
| GSM8024055 |
Gene expression Library, multiplexed |
| GSM8024056 |
Cell multiplexing Library, multiplexed |
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| This SuperSeries is composed of the following SubSeries:
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| GSE253605 |
6 h FGF4 stimulation in Fgf4-mutant and Fgf4; Med12 double mutant mESCs [bulkRNA-seq] |
| GSE253606 |
6 h FGF4 stimulation of Fgf4-mutant mESCs [bulkRNA-seq] |
| GSE253607 |
24 h differentiation in N2B27 of wild-type and Med12-mutant mESCs [bulkRNA-seq] |
| GSE253608 |
Primitive endoderm differentiation in wild-type and Med12-mutant mESCs [scRNA-seq] |
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| Relations |
| BioProject |
PRJNA1066341 |
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