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| Status |
Public on Jun 26, 2024 |
| Title |
Transcriptome analysis to investigate the role of ACLY pathway in senescent cells. |
| Organisms |
Homo sapiens; Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Transcriptome analysis revealed that the inhibition of ACLY pathway supressed the expression of proinflammatory SASP
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| Overall design |
Examination of the role of ACLY pathway in oncogene-induced senescent cells and in aged tissues
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| Contributor(s) |
Etoh K, Nakao M |
| Citation(s) |
39043191 |
| |
| Submission date |
Nov 13, 2023 |
| Last update date |
Sep 25, 2024 |
| Contact name |
Mitsuyoshi Nakao |
| E-mail(s) |
mnakao@gpo.kumamoto-u.ac.jp
|
| Phone |
+81963736800
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| Organization name |
Kumamoto University
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| Department |
Institute of Molecular Embryology and Genetics
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| Lab |
Medical Cell Biology
|
| Street address |
2-2-1 Honjo, Chuo-ku
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| City |
Kumamoto |
| ZIP/Postal code |
860-0811 |
| Country |
Japan |
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| Platforms (2) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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| Samples (56)
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| GSM7897884 |
IMR-90, Qui, rep1 |
| GSM7897885 |
IMR-90, Qui, rep2 |
| GSM7897886 |
IMR-90, Qui, rep3 |
| GSM7897887 |
IMR-90, Sen, rep1 |
| GSM7897888 |
IMR-90, Sen, rep2 |
| GSM7897889 |
IMR-90, Sen, rep3 |
| GSM7897890 |
IMR-90, Pro-Ctrl, rep1 |
| GSM7897891 |
IMR-90, Pro-Ctrl, rep2 |
| GSM7897892 |
IMR-90, Pro-Ctrl, rep3 |
| GSM7897893 |
IMR-90, Sen-Ctrl, rep1 |
| GSM7897894 |
IMR-90, Sen-Ctrl, rep2 |
| GSM7897895 |
IMR-90, Sen-Ctrl, rep3 |
| GSM7897896 |
IMR-90, Sen-siACLY#1, rep1 |
| GSM7897897 |
IMR-90, Sen-siACLY#1, rep2 |
| GSM7897898 |
IMR-90, Sen-siACLY#1, rep3 |
| GSM7897899 |
IMR-90, Sen-siACLY#2, rep1 |
| GSM7897900 |
IMR-90, Sen-siACLY#2, rep2 |
| GSM7897901 |
IMR-90, Sen-siACLY#2, rep3 |
| GSM7897902 |
Liver, Young-veh, rep1 |
| GSM7897903 |
Liver, Young-veh, rep2 |
| GSM7897904 |
Liver, Young-veh, rep3 |
| GSM7897905 |
Liver, Young-veh, rep4 |
| GSM7897906 |
Liver, Old-veh, rep1 |
| GSM7897907 |
Liver, Old-veh, rep2 |
| GSM7897908 |
Liver, Old-veh, rep3 |
| GSM7897909 |
Liver, Old-veh, rep4 |
| GSM7897910 |
Liver, Old-DCV, rep1 |
| GSM7897911 |
Liver, Old-DCV, rep2 |
| GSM7897912 |
Liver, Old-DCV, rep3 |
| GSM7897913 |
Liver, Old-DCV, rep4 |
| GSM7897914 |
Liver, Old-JQ1, rep1 |
| GSM7897915 |
Liver, Old-JQ1, rep2 |
| GSM7897916 |
Liver, Old-JQ1, rep3 |
| GSM7897917 |
Liver, Old-JQ1, rep4 |
| GSM7897918 |
Kidney, Young-veh, rep1 |
| GSM7897919 |
Kidney, Young-veh, rep2 |
| GSM7897920 |
Kidney, Young-veh, rep3 |
| GSM7897921 |
Kidney, Young-veh, rep4 |
| GSM7897922 |
Kidney, Old-veh, rep1 |
| GSM7897923 |
Kidney, Old-veh, rep2 |
| GSM7897924 |
Kidney, Old-veh, rep3 |
| GSM7897925 |
Kidney, Old-veh, rep4 |
| GSM7897926 |
Kidney, Old-DCV, rep1 |
| GSM7897927 |
Kidney, Old-DCV, rep2 |
| GSM7897928 |
Kidney, Old-DCV, rep3 |
| GSM7897929 |
Kidney, Old-DCV, rep4 |
| GSM7897930 |
Kidney, Old-JQ1, rep1 |
| GSM7897931 |
Kidney, Old-JQ1, rep2 |
| GSM7897932 |
Kidney, Old-JQ1, rep3 |
| GSM7897933 |
Kidney, Old-JQ1, rep4 |
| GSM8262185 |
IMR-90, Sen-siRb/p53, rep1 |
| GSM8262186 |
IMR-90, Sen-siRb/p53, rep2 |
| GSM8262187 |
IMR-90, Sen-siRb/p53, rep3 |
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| Relations |
| BioProject |
PRJNA1039809 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE247607_RAW.tar |
27.1 Mb |
(http)(custom) |
TAR (of RESULTS) |
SRA Run Selector |
| Raw data are available in SRA |
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