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| Status |
Public on Nov 01, 2023 |
| Title |
Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma |
| Organisms |
Homo sapiens; Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
This SuperSeries is composed of the SubSeries listed below.
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| Overall design |
Refer to individual Series
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| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Oct 28, 2023 |
| Last update date |
Nov 01, 2023 |
| Contact name |
ZHUXUAN LI |
| E-mail(s) |
liz3@mskcc.org
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| Phone |
6467043994
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| Organization name |
Memorial Sloan Kettering Cancer Center
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| Department |
Cancer Biology and Genetics
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| Lab |
Tuomas Tammela
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| Street address |
417 E 68th St
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| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10065 |
| Country |
USA |
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| Platforms (2) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (33)
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| GSM7869575 |
lung tumor, vehicle, rep 1 |
| GSM7869576 |
lung tumor, vehicle, rep 2 |
| GSM7869577 |
lung tumor, vehicle, rep 3 |
| GSM7869578 |
lung tumor, vehicle, rep 4 |
| GSM7869579 |
lung tumor, cisplatin, rep 4 |
| GSM7869580 |
lung tumor, cisplatin, rep 5 |
| GSM7869581 |
PDX, vehicle, rep 1 |
| GSM7869582 |
PDX, adagrasib, rep 1 |
| GSM7869583 |
PDX, vehicle, rep 2 |
| GSM7869584 |
PDX, adagrasib, rep 2 |
| GSM7869585 |
PDX, vehicle, rep 3 |
| GSM7869586 |
PDX, adagrasib, rep 3 |
| GSM7869587 |
shKras,dox,3days |
| GSM7869588 |
shKras,dox,5days |
| GSM7869589 |
shKras,dox,10days |
| GSM7869590 |
shKras,dox,20days |
| GSM7869591 |
KP,mrtx,5days |
| GSM7869592 |
KP,mrtx,20days |
| GSM7869593 |
shKras,dox,7days |
| GSM7869594 |
subq,MRTX,BFPneg |
| GSM7869595 |
subq,MRTX,BFPpos |
| GSM7869596 |
shKras,dox,3days,HTO |
| GSM7869597 |
shKras,dox,5days,HTO |
| GSM7869598 |
shKras,dox,10days,HTO |
| GSM7869599 |
shKras,dox,20days,HTO |
| GSM7869600 |
KP,mrtx,5days,HTO |
| GSM7869601 |
KP,mrtx,20days,HTO |
| GSM7869602 |
shKras,dox,7days,HTO |
| GSM7869603 |
subq,MRTX,BFPneg,HTO |
| GSM7869604 |
subq,MRTX,BFPpos,HTO |
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| This SuperSeries is composed of the following SubSeries: |
| GSE246480 |
Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma [RNA-seq] |
| GSE246481 |
Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma [scRNA-seq] |
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| Relations |
| BioProject |
PRJNA1033182 |
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