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| Status |
Public on Jan 12, 2024 |
| Title |
Single-nucleus RNA-seq of aortas from Ldlr-/- and Ldlr-/-Trem2-/- atherosclerotic mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Single-nucleus RNA-seq of aortas was performed in Ldlr-/- and Ldlr-/-Trem2-/- mice fed a high fat diet for 10 weeks
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| Overall design |
Ldlr-/- (n=3) and Ldlr-/-Trem2-/- (n=3) female mice were fed a high fat diet for 10 weeks to induce the formation of atherosclerotic plaques. Aortas were excised, cryoconserved and nuclei extracted for single-nucleus RNA-sequencing
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| Web link |
https://doi.org/10.1038/s44161-024-00429-9
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| |
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| Contributor(s) |
Cochain C, Krammer T, Saliba A, Leipold A |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Sep 13, 2023 |
| Last update date |
Jun 07, 2024 |
| Contact name |
Alexander M. Leipold |
| Organization name |
Helmholtz Institute for RNA-based Infection Research
|
| Lab |
Saliba Lab
|
| Street address |
Josef-Schneider-Str. 2
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| City |
Würzburg |
| ZIP/Postal code |
97080 |
| Country |
Germany |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA1016340 |
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