NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE241990 Query DataSets for GSE241990
Status Public on Jul 17, 2024
Title The murine 900 kb downsteam region from Gata3 interacts to the transciption start site and three enhancers in Th2 cells.
Organism Mus musculus
Experiment type Other
Summary Murine counterpart of the region (mG900 region), in which SNPs associated with human asthma are enriched, is located 900 kb downstream from the transcription start site (TSS) of Gata3. Gata3-TSS interacted with mG900 region in only cultured Th2 cells but not in naive CD4 T cells or cultured Th0 cells. The mG900-deficient Th2 cells exhibited reduced interaction between Gata3-TSS and three enhancers.
 
Overall design 4C-seq were perfromed for cultured CD4 T cells using two baits of transcription start site of Gata3 and the region located at 932 downstream from Gata3.
 
Contributor(s) Iwata A, Okabe A
Citation(s) 38923989
Submission date Aug 30, 2023
Last update date Jul 18, 2024
Contact name Arifumi Iwata
Organization name Chiba University
Department Department of Allergy and Clinical Immunology
Street address 1-8-1 Inohana, Chuou-ku
City Chiba-shi
State/province Chiba
ZIP/Postal code 260-8670
Country Japan
 
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (7)
GSM7747241 4Cseq_Gata3-TSS_WT_Naive
GSM7747242 4Cseq_Gata3-TSS_WT_Th0
GSM7747243 4Cseq_Gata3-TSS_WT_Th2
Relations
BioProject PRJNA1010862

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE241990_RAW.tar 20.0 Kb (http)(custom) TAR (of BED)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap