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Series GSE23952 Query DataSets for GSE23952
Status Public on Sep 03, 2010
Title Expression data from TGF-beta treated Panc-1 pancreatic adenocarcinoma cell line
Organism Homo sapiens
Experiment type Expression profiling by array
Summary TGF-beta treatment of Panc-1 pancreatic adenocarcinoma cell line on Affymetrix HG_U133_plus_2 arrays; triplicate experiments.
The goal of the experiment is to profile temporal gene expression changes during TGF-beta-induced epithelial-mesenchymal transition (EMT). During EMT cancer cells lose their epithelial specifc proteins and gain mesenchymal proteins to acquire migratory and invasive phenotype essential for metastasis. Human Panc-1 pancreatic adenocarcinoma cell line was treated with 5 ng/mL TGF-beta for 48 h to induce EMT. The experiment was repeated 3 times. Samples were assayed using Affymetrix HG_U133_plus_2 arrays with 54675 probe-sets, using standard techniques.
 
Overall design Human Panc-1 pancreatic adenocarcinoma cell line was treated with 5 ng/mL TGF-beta for 48 h. The experiment was repeated 3 times. Samples were assayed using Affymetrix HG_U133_plus_2 arrays with 54675 probe-sets, using standard techniques.
 
Contributor(s) Sartor MA, Mahavisno V, Keshamouni VG, Cavalcoli J, Wright Z, Karnovsky A, Kuick R, Jagadish H, Mirel B, Weymouth T, Athey B, Omenn GS
Citation(s) 20885998
Submission date Sep 02, 2010
Last update date Mar 25, 2019
Contact name brian haab
E-mail(s) brian.haab@vai.org
Phone 6162345268
Organization name van andel institute
Department lab of cancer immunodiagnostics
Street address 333 bostwick avenue NE
City grand rapids
State/province MI
ZIP/Postal code 49503
Country USA
 
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (6)
GSM590166 Panc-1 Untreated Control 1
GSM590167 Panc-1 Untreated Control 2
GSM590168 Panc-1 Untreated Control 3
Relations
BioProject PRJNA130493

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SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE23952_RAW.tar 28.7 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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