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| Status |
Public on Sep 03, 2010 |
| Title |
Expression data from TGF-beta treated Panc-1 pancreatic adenocarcinoma cell line |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
TGF-beta treatment of Panc-1 pancreatic adenocarcinoma cell line on Affymetrix HG_U133_plus_2 arrays; triplicate experiments.
The goal of the experiment is to profile temporal gene expression changes during TGF-beta-induced epithelial-mesenchymal transition (EMT). During EMT cancer cells lose their epithelial specifc proteins and gain mesenchymal proteins to acquire migratory and invasive phenotype essential for metastasis. Human Panc-1 pancreatic adenocarcinoma cell line was treated with 5 ng/mL TGF-beta for 48 h to induce EMT. The experiment was repeated 3 times. Samples were assayed using Affymetrix HG_U133_plus_2 arrays with 54675 probe-sets, using standard techniques.
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| Overall design |
Human Panc-1 pancreatic adenocarcinoma cell line was treated with 5 ng/mL TGF-beta for 48 h. The experiment was repeated 3 times. Samples were assayed using Affymetrix HG_U133_plus_2 arrays with 54675 probe-sets, using standard techniques.
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| Contributor(s) |
Sartor MA, Mahavisno V, Keshamouni VG, Cavalcoli J, Wright Z, Karnovsky A, Kuick R, Jagadish H, Mirel B, Weymouth T, Athey B, Omenn GS |
| Citation(s) |
20885998 |
| Submission date |
Sep 02, 2010 |
| Last update date |
Mar 25, 2019 |
| Contact name |
brian haab |
| E-mail(s) |
brian.haab@vai.org
|
| Phone |
6162345268
|
| Organization name |
van andel institute
|
| Department |
lab of cancer immunodiagnostics
|
| Street address |
333 bostwick avenue NE
|
| City |
grand rapids |
| State/province |
MI |
| ZIP/Postal code |
49503 |
| Country |
USA |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA130493 |
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