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Status |
Public on Aug 16, 2010 |
Title |
Population genetic structure of the Ashkenazi Jewish population |
Organism |
Homo sapiens |
Experiment type |
Genome variation profiling by SNP array
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Summary |
The Ashkenazi Jewish population has long been considered a genetic isolate and presumed to have the genetic signatures of founder effects and isolation. We genotyped a large cohort of Ashkenazi Jews and analyzed their genetic structure compared to other worldwide populations.
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Overall design |
We genotyped 471 normal control Ashkenazi Jewish individuals with the Affymetrix 6.0 array and analyzed their genetic structure relative to other Europe and worldwide populations. We measured heterozygosity, linkage disequilibrium, identity-by-descent and used extended haplotype tests of positive selection.
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Contributor(s) |
Steven M. B, Stephen T. W |
Citation(s) |
20798349 |
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Submission date |
Aug 16, 2010 |
Last update date |
Nov 27, 2018 |
Contact name |
Steven M Bray |
E-mail(s) |
smbray@emory.edu
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Organization name |
Emory University School of Medicine
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Department |
Human Genetics
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Street address |
615 Michael Street
|
City |
Atlanta |
State/province |
GA |
ZIP/Postal code |
30322 |
Country |
USA |
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Platforms (1) |
GPL6801 |
[GenomeWideSNP_6] Affymetrix Genome-Wide Human SNP 6.0 Array |
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Samples (471)
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Relations |
BioProject |
PRJNA130941 |