|
| Status |
Public on Aug 16, 2010 |
| Title |
Population genetic structure of the Ashkenazi Jewish population |
| Organism |
Homo sapiens |
| Experiment type |
Genome variation profiling by SNP array
|
| Summary |
The Ashkenazi Jewish population has long been considered a genetic isolate and presumed to have the genetic signatures of founder effects and isolation. We genotyped a large cohort of Ashkenazi Jews and analyzed their genetic structure compared to other worldwide populations.
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| |
|
| Overall design |
We genotyped 471 normal control Ashkenazi Jewish individuals with the Affymetrix 6.0 array and analyzed their genetic structure relative to other Europe and worldwide populations. We measured heterozygosity, linkage disequilibrium, identity-by-descent and used extended haplotype tests of positive selection.
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| |
|
| Contributor(s) |
Steven M. B, Stephen T. W |
| Citation(s) |
20798349 |
| |
| Submission date |
Aug 16, 2010 |
| Last update date |
Nov 27, 2018 |
| Contact name |
Steven M Bray |
| E-mail(s) |
smbray@emory.edu
|
| Organization name |
Emory University School of Medicine
|
| Department |
Human Genetics
|
| Street address |
615 Michael Street
|
| City |
Atlanta |
| State/province |
GA |
| ZIP/Postal code |
30322 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6801 |
[GenomeWideSNP_6] Affymetrix Genome-Wide Human SNP 6.0 Array |
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| Samples (471)
|
|
| Relations |
| BioProject |
PRJNA130941 |
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