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| Status |
Public on Nov 30, 2023 |
| Title |
Gene expression profile at single nucleus level of the generated neural concentroids with or without vascularization |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We generated homogeneous neural constructs called neural concentroids. We used single nucleus RNA sequencing (snRNA-seq) to analyze the diversity of brain cell types in the neural concentroids with or without the incorporation of hiPSC-derived endothelial cells as an effect of vascularization
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| Overall design |
Cell nuclei were isolated by in-house protocols and analyzed using snRNAseq.
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| Contributor(s) |
Chai YC, To SK, Simorgh S, Zaunz S, Zhu Y, Ahuja K, Lemaitre A, Ramezankhani R, van der Veer BK, Wierda K, Verhulst S, van Grunsven LA, Pasque V, Verfaillie C |
| Citation(s) |
38037510 |
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| Submission date |
May 30, 2023 |
| Last update date |
Feb 15, 2024 |
| Contact name |
Yoke Chin Chai |
| E-mail(s) |
yoke.chin.chai@imec.be
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| Organization name |
KU Leuven
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| Department |
Development & Regeneration
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| Lab |
Stem Cell Institute Leuven
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| Street address |
Herestraat 49, ON5
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| City |
Leuven |
| State/province |
Leuven |
| ZIP/Postal code |
3000 |
| Country |
Belgium |
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| Platforms (1) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA977683 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE233741_RAW.tar |
119.8 Mb |
(http)(custom) |
TAR (of RDS) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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