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| Status |
Public on Feb 14, 2024 |
| Title |
Global transcriptomic analysis of placenta from women with gestational SARS-CoV-2 infection during the 3rd trimester of pregnancy |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Transcriptomic analysis of the placenta in both maternal and fetal compartments was performed to investigate the impact of maternal SARS-CoV-2 infection.
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| Overall design |
16 placental samples from women immediately after term delivery were collected, of which seven had confirmed SARS-CoV-2 infection by PCR before parturition. Extracted total RNA from placental tissues, separately from maternal and fetal compartments, constructed cDNA libraries, and sequenced them to assess mRNA and small RNA expression.
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| Contributor(s) |
Rao Boggavarapu N |
| Citation(s) |
38338886 |
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| Submission date |
May 26, 2023 |
| Last update date |
Feb 14, 2024 |
| Contact name |
Nageswara Rao Boggavarapu |
| E-mail(s) |
nagsdsh@gmail.com
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| Organization name |
Karolinska Institutet
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| Department |
Women and Children health
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| Lab |
Bioclinicum J9:30
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| Street address |
Visionsgatan 4
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| City |
Solna |
| State/province |
stockholm |
| ZIP/Postal code |
17164 |
| Country |
Sweden |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (27)
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| GSM7430323 |
Sars-CoV-2 Placenta, 14M, RNA-seq |
| GSM7430324 |
Sars-CoV-2 Placenta, 16M, RNA-seq |
| GSM7430325 |
Sars-CoV-2 Placenta, 17M, RNA-seq |
| GSM7430326 |
Sars-CoV-2 Placenta, 1M, RNA-seq |
| GSM7430327 |
Control Placenta, 2M, RNA-seq |
| GSM7430328 |
Control Placenta, 3M, RNA-seq |
| GSM7430329 |
Sars-CoV-2 Placenta, 4M, RNA-seq |
| GSM7430330 |
Control Placenta, 5M, RNA-seq |
| GSM7430331 |
Control Placenta, 7M, RNA-seq |
| GSM7430332 |
Control Placenta, 8M, RNA-seq |
| GSM7430333 |
Control Placenta, 9M, RNA-seq |
| GSM7430334 |
Control Placenta, 11F, RNA-seq |
| GSM7430335 |
Control Placenta, 12F, RNA-seq |
| GSM7430336 |
Sars-CoV-2 Placenta, 14F, RNA-seq |
| GSM7430337 |
Sars-CoV-2 Placenta, 15F, RNA-seq |
| GSM7430338 |
Sars-CoV-2 Placenta, 16F, RNA-seq |
| GSM7430339 |
Sars-CoV-2 Placenta, 17F, RNA-seq |
| GSM7430340 |
Sars-CoV-2 Placenta, 1F, RNA-seq |
| GSM7430341 |
Control Placenta, 2F, RNA-seq |
| GSM7430342 |
Control Placenta, 3F, RNA-seq |
| GSM7430343 |
Sars-CoV-2 Placenta, 4F, RNA-seq |
| GSM7430344 |
Control Placenta, 5F, RNA-seq |
| GSM7430345 |
Control Placenta, 7F, RNA-seq |
| GSM7430346 |
Control Placenta, 9F, RNA-seq |
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| Relations |
| BioProject |
PRJNA976658 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE233557_Fetal_Raw_Counts.txt.gz |
692.3 Kb |
(ftp)(http) |
TXT |
| GSE233557_Fetal_filtered_counts.txt.gz |
903.1 Kb |
(ftp)(http) |
TXT |
| GSE233557_Maternal_Normalised_counts.txt.gz |
844.5 Kb |
(ftp)(http) |
TXT |
| GSE233557_Maternal_Raw_Counts.txt.gz |
609.7 Kb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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