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Status |
Public on Mar 01, 2024 |
Title |
A human iPSC-derived multilineage liver organoid model containing Kupffer cells to study human sepsis-associated liver dysfunction [hiPSC-EMP-KC-pKC] |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
To incorporate Kupffer cells into hiPSC-LOs, we differentiated erythro-myeloid progenitors (EMPs) from hiPSCs. We compares the gene expression profiles of hiPSC-EMPs with cord-blood hematopoietic stem and progenitor cells (CB-HSPCs); and EMP-generated Kupffer cells (EMP-KC) with human primary Kupffer cells.
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Overall design |
Comparative gene expression profiling analysis of RNA-seq data for hiPSC, hiPSC-EMP, CB-HSPC, EMP-derived kupffer cells, and primary Kupffer cells.
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Web link |
https://pubmed.ncbi.nlm.nih.gov/38451817/
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Contributor(s) |
Li Y, Nie Y, Taniguchi H |
Citation(s) |
38451817 |
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Submission date |
May 26, 2023 |
Last update date |
Jun 02, 2024 |
Contact name |
Yang Li |
E-mail(s) |
liyang.fdu@yahoo.com
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Organization name |
The University of Tokyo
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Street address |
Shirokanedai 4-6-1
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City |
Minato |
State/province |
Tokyo |
ZIP/Postal code |
1080071 |
Country |
Japan |
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Platforms (1) |
GPL17303 |
Ion Torrent Proton (Homo sapiens) |
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Samples (12)
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This SubSeries is part of SuperSeries: |
GSE233539 |
A human iPSC-derived multilineage liver organoid model containing Kupffer cells to study human sepsis-associated liver dysfunction |
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Relations |
BioProject |
PRJNA976631 |
Supplementary file |
Size |
Download |
File type/resource |
GSE233538_Combined_processed_data_hiPSC-EMP-KC.xlsx |
2.2 Mb |
(ftp)(http) |
XLSX |
SRA Run Selector |
Raw data are available in SRA |
Processed data are available on Series record |
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