|
| Status |
Public on Jun 28, 2023 |
| Title |
Immunoglobulin repertoires in mice carrying a knock-in human Cµ gene downstream of the IGH 3' regulatory region |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To in-depth analyze the repertoire of B cells after the occurrence of recombination events joining SÙ to the IgH downstream regulatory region (3'RR)
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| |
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| Overall design |
Spleen B cell RNA samples from knock-in mice, comparing the endogenous IgM µ heavy chain transcripts (VDJ spliced onto MmCµ), versus endogenous mouse spliced IgG2b gamma heavy chain transcripts (VDJ spliced to MmG2b), versus spliced VDJ-hCµ transcripts obtained after recombination close to the ectopic knock-in human Cµ gene
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| |
|
| Contributor(s) |
Cogné M, ROSSILLE D |
| Citation(s) |
37359540 |
| |
| Submission date |
May 25, 2023 |
| Last update date |
Jun 29, 2023 |
| Contact name |
Delphine Rossille |
| E-mail(s) |
delphine.rossille@univ-rennes1.fr
|
| Organization name |
INSERM U1236-MOBIDIC
|
| Street address |
2 avenue du Pr. Léon Bernard
|
| City |
Rennes |
| ZIP/Postal code |
35000 |
| Country |
France |
| |
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| Platforms (1) |
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| Samples (33)
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|
| Relations |
| BioProject |
PRJNA976398 |
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