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| Status |
Public on Nov 20, 2023 |
| Title |
A multiscale 3D chromatin architecture that controls development of the humoral immune system is assembled by IKAROS |
| Organisms |
Homo sapiens; Mus musculus |
| Experiment type |
Other
Genome binding/occupancy profiling by high throughput sequencing
Expression profiling by high throughput sequencing
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| Summary |
This SuperSeries is composed of the SubSeries listed below.
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| Overall design |
Refer to individual Series
Grant ID: NIH T32 AI007512
Grant title: Molecular Basis of Allergic and Immunologic Disease
Affiliation: Children's Hospital
Name: Yeguang Hu
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| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R01 HL140622 |
Ikaros regulation: Study on hemolymphopoiesis |
MASSACHUSETTS GENERAL HOSPITAL |
Katia Georgopoulos |
| R01 AR069132 |
Epigenetic regulation of proinflammatory responses in the skin |
MASSACHUSETTS GENERAL HOSPITAL |
Katia Georgopoulos |
| R56 AR082402 |
Epigenetic regulation of epidermal proinflammatory responses |
MASSACHUSETTS GENERAL HOSPITAL |
Katia Georgopoulos |
| R35 GM128938 |
Studying the function of human genetic variation in the light of 3D genome organization |
LA JOLLA INSTITUTE FOR IMMUNOLOGY |
Ferhat Ay |
| R21 AR074748 |
Molecular genetics of eccrine sweat gland development |
MASSACHUSETTS GENERAL HOSPITAL |
Bruce A Morgan |
| R01 AI150860 |
Role of CXCR4 in immunoglobulin light chain recombination |
UNIVERSITY OF CHICAGO |
Marcus Ramsay Clark |
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| |
| Submission date |
May 13, 2023 |
| Last update date |
Mar 13, 2024 |
| Contact name |
Katia Georgopoulos |
| E-mail(s) |
katia.georgopoulos@cbrc2.mgh.harvard.edu
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| Phone |
617-7264445
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| Organization name |
Harvard Medical School
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| Department |
CBRC
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| Lab |
Georgopoulos
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| Street address |
1st and 13th St
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| City |
Charlestown |
| State/province |
MA |
| ZIP/Postal code |
02129 |
| Country |
USA |
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| Platforms (5)
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| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (120)
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| GSM7305476 |
Large preB, IKDN, rep 2 |
| GSM7305477 |
Large preB_inducible IkE5 deletion, DMSO Ctl/D0 |
| GSM7305478 |
Large preB_inducible IkE5 deletion, 4OHT induction D4 |
| GSM7305479 |
Large preB_inducible IkE5 deletion, 4OHT induction D12 |
| GSM7305480 |
Large preB_inducible IkE5 deletion, 4OHT induction D18 |
| GSM7305481 |
HaCaT_Tet-on-Luc, Dox Day2 |
| GSM7305482 |
HaCaT_Tet-on-Luc, Dox Day3 |
| GSM7305483 |
HaCaT_Tet-on-Ikzf1, Dox Day2 |
| GSM7305484 |
HaCaT_Tet-on-Ikzf1, Dox Day3 |
| GSM7305485 |
Large preB cell, WT, H3K27ac HiChIP, rep1 |
| GSM7305486 |
Large preB cell, IKDN, H3K27ac HiChIP, rep1 |
| GSM7305487 |
Large preB cell, WT, H3K27ac HiChIP, rep2 |
| GSM7305488 |
Large preB cell, IKDN, H3K27ac HiChIP, rep2 |
| GSM7305489 |
Large preB cell, WT, CTCF HiChIP, rep1 |
| GSM7305490 |
Large preB cell, IKDN, CTCF HiChIP, rep1 |
| GSM7305491 |
Large preB cell, WT, CTCF HiChIP, rep2 |
| GSM7305492 |
Large preB cell, IKDN, CTCF HiChIP, rep2 |
| GSM7305493 |
Large preB cell, WT, SMC1a HiChIP, rep1 |
| GSM7305494 |
Large preB cell, IKDN, SMC1a HiChIP, rep1 |
| GSM7305495 |
Large preB cell, WT, SMC1a HiChIP, rep2 |
| GSM7305496 |
Large preB cell, IKDN, SMC1a HiChIP, rep2 |
| GSM7305497 |
Large preB cell, WT, IKAROS HiChIP, rep1 |
| GSM7305498 |
Large preB_inducible IkE5 deletion, DMSO control, H3K27ac HiChIP, rep1 |
| GSM7305499 |
Large preB_inducible IkE5 deletion, 4OHT induction day3, H3K27ac HiChIP, rep1 |
| GSM7305500 |
Large preB_inducible IkE5 deletion, 4OHT induction day12, H3K27ac HiChIP, rep1 |
| GSM7305501 |
Large preB_inducible IkE5 deletion, DMSO control, H3K27ac HiChIP, rep2 |
| GSM7305502 |
Large preB_inducible IkE5 deletion, 4OHT induction day3, H3K27ac HiChIP, rep2 |
| GSM7305503 |
Large preB_inducible IkE5 deletion, 4OHT induction day12, H3K27ac HiChIP, rep2 |
| GSM7305504 |
Large preB_inducible IkE5 deletion, DMSO control, CTCF HiChIP, replicate 1 |
| GSM7305505 |
Large preB_inducible IkE5 deletion, 4OHT induction day3, CTCF HiChIP, rep1 |
| GSM7305506 |
Large preB_inducible IkE5 deletion, 4OHT induction day12, CTCF HiChIP, rep1 |
| GSM7305507 |
HaCaT_Tet-on-Luc, DoxD3, H3K27ac HiChIP |
| GSM7305508 |
HaCaT_Tet-on-Ikzf1, DoxD3, H3K27ac HiChIP |
| GSM7305509 |
HaCaT_Tet-on-Luc, DoxD3, CTCF HiChIP |
| GSM7305510 |
HaCaT_Tet-on-kzf1, DoxD3, CTCF HiChIP |
| GSM7305511 |
HaCaT_Tet-on-Ikzf1, DoxD3, IKAROS HiChIP, rep1 |
| GSM7305512 |
HaCaT_Tet-on-Ikzf1, DoxD3, IKAROS HiChIP, rep2 |
| GSM7310680 |
HaCaT_Tet-on-Luc, DoxD3, H3K4me1 |
| GSM7310681 |
HaCaT_Tet-on-Ikzf1, DoxD3, H3K4me1 |
| GSM7310682 |
HaCaT_Tet-on-Luc, DoxD3, H3K4me3 |
| GSM7310683 |
HaCaT_Tet-on-Ikzf1, DoxD3, H3K4me3 |
| GSM7310684 |
HaCaT_Tet-on-Luc, DoxD3, H3K27ac |
| GSM7310685 |
HaCaT_Tet-on-Ikzf1, DoxD3, H3K27ac |
| GSM7310686 |
HaCaT_Tet-on-Luc, DoxD3, CTCF |
| GSM7310687 |
HaCaT_Tet-on-Ikzf1, DoxD3, CTCF |
| GSM7310688 |
HaCaT_Tet-on-Luc, DoxD3, SMC1A |
| GSM7310689 |
HaCaT_Tet-on-Ikzf1, DoxD3, SMC1A |
| GSM7310690 |
HaCaT_Tet-on-Ikzf1, DoxD3, IKAROS |
| GSM7310691 |
HaCaT_Tet-on-Luc, DoxD3, Input |
| GSM7310692 |
HaCaT_Tet-on-Ikzf1, DoxD3, Input |
| GSM7310818 |
HaCaT_Tet-on-Luc, Dox-, rep1 |
| GSM7310819 |
HaCaT_Tet-on-Ikzf1, Dox+, Day1, rep1 |
| GSM7310820 |
HaCaT_Tet-on-Ikzf1, Dox+, Day2, rep1 |
| GSM7310821 |
HaCaT_Tet-on-Ikzf1, Dox+, Day3, rep1 |
| GSM7310822 |
HaCaT_Tet-on-Luc, Dox-, rep2 |
| GSM7310823 |
HaCaT_Tet-on-Ikzf1, Dox+, Day1, rep2 |
| GSM7310824 |
HaCaT_Tet-on-Ikzf1, Dox+, Day2, rep2 |
| GSM7310825 |
HaCaT_Tet-on-Ikzf1, Dox+, Day3, rep2 |
| GSM7310826 |
HaCaT_Tet-on-Luc, Dox+, Day3, rep1 |
| GSM7310827 |
HaCaT_Tet-on-Luc, Dox+, Day3, rep2 |
| GSM7310828 |
Large preB cell, WT, rep1 |
| GSM7310829 |
Large preB cell, IKDN, rep1 |
| GSM7310830 |
Large preB cell, WT, rep2 |
| GSM7310831 |
Large preB cell, IKDN, rep2 |
| GSM7336789 |
Large preB cell, WT, CTCF, rep1 |
| GSM7336790 |
Large preB cell, IKDN, CTCF, rep1 |
| GSM7336791 |
Large preB cell, WT, CTCF, rep2 |
| GSM7336792 |
Large preB cell, IKDN, CTCF, rep2 |
| GSM7336793 |
Large preB cell, WT, SMC1A, rep1 |
| GSM7336794 |
Large preB cell, IKDN, SMC1A, rep1 |
| GSM7336795 |
Large preB cell, WT, SMC1A, rep2 |
| GSM7336796 |
Large preB cell, IKDN, SMC1A, rep2 |
| GSM7336797 |
Large preB cell, WT, IKAROS, rep1 |
| GSM7336798 |
Large preB cell, WT, IKAROS, rep2 |
| GSM7336799 |
Large preB cell, WT, H3K4me3, rep1 |
| GSM7336800 |
Large preB cell, IKDN, H3K4me3, rep1 |
| GSM7336801 |
Large preB cell, WT, H3K4me3, rep2 |
| GSM7336802 |
Large preB cell, IKDN, H3K4me3, rep2 |
| GSM7336803 |
Large preB cell, WT, IL7 withdrawal day2, H3K4me3, rep1 |
| GSM7336804 |
Large preB cell, WT, IL7 withdrawal day2 H3K4me3, rep2 |
| GSM7336805 |
Large preB cell, WT, H3K27ac, rep1 |
| GSM7336806 |
Large preB cell, IKDN, H3K27ac,rep1 |
| GSM7336807 |
Large preB cell, WT, H3K27ac, rep2 |
| GSM7336808 |
Large preB cell, IKDN, H3K27ac,rep2 |
| GSM7336809 |
Large preB cell, WT, H3K4me1 |
| GSM7336810 |
Large preB cell, IKDN, H3K4me1 |
| GSM7336811 |
Large preB cell, WT, H3K36me3 |
| GSM7336812 |
Large preB cell, IKDN, H3K36me3 |
| GSM7336813 |
Large preB cell, WT, Input |
| GSM7336814 |
Large preB cell, IKDN, Input |
| GSM7336815 |
Large preB cell, inducible IkE5 deletion, DMSO/Induction D0, H3K27ac, rep1 |
| GSM7336816 |
Large preB cell, inducible IkE5 deletion, 4OHT induction D3, H3K27ac, rep1 |
| GSM7336817 |
Large preB cell, inducible IkE5 deletion, 4OHT induction D12, H3K27ac, rep1 |
| GSM7336818 |
Large preB cell, inducible IkE5 deletion, DMSO/Induction D0, H3K27ac, rep2 |
| GSM7336819 |
Large preB cell, inducible IkE5 deletion, 4OHT induction D3, H3K27ac, rep2 |
| GSM7336820 |
Large preB cell, inducible IkE5 deletion, 4OHT induction D12, H3K27ac, rep2 |
| GSM7336821 |
Large preB cell, inducible IkE5 deletion, DMSO/Induction D0, CTCF, rep1 |
| GSM7336822 |
Large preB cell, inducible IkE5 deletion, 4OHT induction D3, CTCF, rep1 |
| GSM7336823 |
Large preB cell, inducible IkE5 deletion, 4OHT induction D12, CTCF, rep1 |
| GSM7336824 |
Large preB cell, inducible IkE5 deletion, DMSO/Induction D0, CTCF, rep2 |
| GSM7336825 |
Large preB cell, inducible IkE5 deletion, 4OHT induction D3, CTCF, rep2 |
| GSM7336826 |
Large preB cell, inducible IkE5 deletion, 4OHT induction D12, CTCF, rep2 |
| GSM7336827 |
Large preB cell, inducible IkE5 deletion, DMSO/Induction D0, input |
| GSM7336828 |
Large preB cell, inducible IkE5 deletion, 4OHT induction D3, Input |
| GSM7336829 |
Large preB cell, inducible IkE5 deletion, 4OHT induction D12, Input |
| GSM7646192 |
Large preB cell, WT, NIPBL, rep1 |
| GSM7646193 |
Large preB cell, IKDN, NIPBL, rep1 |
| GSM7646194 |
Large preB cell, WT, NIPBL, rep2 |
| GSM7646195 |
Large preB cell, IKDN, NIPBL, rep2 |
| GSM7646196 |
splenic immature B cell, WT, rep1 |
| GSM7646197 |
splenic immature B cell, WT, rep2 |
| GSM7646198 |
splenic B1a cell, WT, rep1 |
| GSM7646199 |
splenic B1a cell, WT, rep2 |
| GSM7646200 |
splenic marginal zone B cell, WT, rep 1 |
| GSM7646201 |
splenic marginal zone B cell, WT, rep 2 |
| GSM7646202 |
splenic folliculaar B cell, WT, rep1 |
| GSM7646203 |
splenic folliculaar B cell, WT, rep2 |
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| This SuperSeries is composed of the following SubSeries:
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| GSE231876 |
A multiscale 3D chromatin architecture that controls development of the humoral immune system is assembled by IKAROS [HiC_LpreB_Steadystate] |
| GSE231877 |
A multiscale 3D chromatin architecture that controls development of the humoral immune system is assembled by IKAROS [HiC_LpreB_Inducible_deletion] |
| GSE231878 |
A multiscale 3D chromatin architecture that controls development of the humoral immune system is assembled by IKAROS [Hi-C_HaCaT] |
| GSE231879 |
A multiscale 3D chromatin architecture that controls development of the humoral immune system is assembled by IKAROS [HiChIP_LpreB steady state] |
| GSE231880 |
A multiscale 3D chromatin architecture that controls development of the humoral immune system is assembled by IKAROS [HiChIP_LpreB_Inducible] |
| GSE231881 |
A multiscale 3D chromatin architecture that controls development of the humoral immune system is assembled by IKAROS [HiChIP_HaCaT] |
| GSE232038 |
A multiscale 3D chromatin architecture that controls development of the humoral immune system is assembled by IKAROS [ChIP-seq HaCaT] |
| GSE232041 |
A multiscale 3D chromatin architecture that controls development of the humoral immune system is assembled by IKAROS [RNA-seq HaCaT] |
| GSE232042 |
A multiscale 3D chromatin architecture that controls development of the humoral immune system is assembled by IKAROS [RNA-seq LpreB] |
| GSE232463 |
A multiscale 3D chromatin architecture that controls development of the humoral immune system is assembled by IKAROS [ChIP-seq LpreB cell] |
| GSE237724 |
A multiscale 3D chromatin architecture that controls development of the humoral immune system is assembled by IKAROS [ChIP-Seq 3] |
| GSE237725 |
A multiscale 3D chromatin architecture that controls development of the humoral immune system is assembled by IKAROS [RNA-Seq 3] |
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| Relations |
| BioProject |
PRJNA972312 |
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