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| Status |
Public on Nov 01, 2023 |
| Title |
Comparison of T cell response to S. aureus and E. coli derived virulence determinants using RNA sequencing |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We aimed to compare transcriptomic changes in T cells in response to sterile bacterial culture supernatants derived from different E.coli and S.aureus strains. Gene expression was analyzed at two different time points.
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| Overall design |
Jurkat T cells were treated with sterile supernatants from bacterial overnight cultures or left untreated as control. Two S.aureus strains (USA300, ST398) and three E.coli strains (536, IHE3034, MG1655) were used. RNA was isolated 1h and 6h after exposure. Three biological replicates per treatment were included.
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| Contributor(s) |
vom Werth KL, Huge A, Kampmeier S, Mellmann A |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
May 10, 2023 |
| Last update date |
Nov 01, 2023 |
| Contact name |
Kari Lavinia vom Werth |
| E-mail(s) |
karilavinia.vomwerth@ukmuenster.de
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| Organization name |
University Hospital Münster
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| Department |
Institute of Hygiene
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| Street address |
Robert-Koch-Str. 41
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| City |
Münster |
| ZIP/Postal code |
48149 |
| Country |
Germany |
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| Platforms (1) |
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| Samples (39)
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| GSM7316614 |
Ctrl, 1h, R1 |
| GSM7316615 |
Ctrl, 1h, R2 |
| GSM7316616 |
Ctrl, 1h, R3 |
| GSM7316617 |
Ctrl, 6h, R1 |
| GSM7316618 |
Ctrl, 6h, R2 |
| GSM7316619 |
Ctrl, 6h, R3 |
| GSM7316620 |
USA300, 1h, R1 |
| GSM7316621 |
USA300, 1h, R2 |
| GSM7316622 |
USA300, 1h, R3 |
| GSM7316623 |
USA300, 6h, R1 |
| GSM7316624 |
USA300, 6h, R2 |
| GSM7316625 |
USA300, 6h, R3 |
| GSM7316626 |
ST398, 1h, R1 |
| GSM7316627 |
ST398, 1h, R2 |
| GSM7316628 |
ST398, 1h, R3 |
| GSM7316629 |
ST398, 6h, R1 |
| GSM7316630 |
ST398, 6h, R2 |
| GSM7316631 |
ST398, 6h, R3 |
| GSM7316632 |
536, 1h, R1 |
| GSM7316633 |
536, 1h, R2 |
| GSM7316634 |
536, 1h, R3 |
| GSM7316635 |
536, 6h, R1 |
| GSM7316636 |
536, 6h, R2 |
| GSM7316637 |
536, 6h, R3 |
| GSM7316638 |
IHE3034, 1h, R1 |
| GSM7316639 |
IHE3034, 1h, R2 |
| GSM7316640 |
IHE3034, 1h, R3 |
| GSM7316641 |
IHE3034, 6h, R1 |
| GSM7316642 |
IHE3034, 6h, R2 |
| GSM7316643 |
IHE3034, 6h, R3 |
| GSM7316644 |
MG1655, 1h, R1 |
| GSM7316645 |
MG1655, 1h, R2 |
| GSM7316646 |
MG1655, 1h, R3 |
| GSM7316647 |
MG1655, 6h, R1 |
| GSM7316648 |
MG1655, 6h, R2 |
| GSM7316649 |
MG1655, 6h, R3 |
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| Relations |
| BioProject |
PRJNA971149 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE232159_Deseq2_536_1h_vs_Ctrl_1h.txt.gz |
5.2 Mb |
(ftp)(http) |
TXT |
| GSE232159_Deseq2_536_6h_vs_Ctrl_6h.txt.gz |
5.2 Mb |
(ftp)(http) |
TXT |
| GSE232159_Deseq2_IHE3034_1h_vs_Ctrl_1h.txt.gz |
5.3 Mb |
(ftp)(http) |
TXT |
| GSE232159_Deseq2_IHE3034_6h_vs_Ctrl_6h.txt.gz |
5.3 Mb |
(ftp)(http) |
TXT |
| GSE232159_Deseq2_MG1655_1h_vs_Ctrl_1h.txt.gz |
5.2 Mb |
(ftp)(http) |
TXT |
| GSE232159_Deseq2_MG1655_6h_vs_Ctrl_6h.txt.gz |
5.2 Mb |
(ftp)(http) |
TXT |
| GSE232159_Deseq2_ST398_1h_vs_Ctrl_1h.txt.gz |
5.2 Mb |
(ftp)(http) |
TXT |
| GSE232159_Deseq2_ST398_6h_vs_Ctrl_6h.txt.gz |
5.2 Mb |
(ftp)(http) |
TXT |
| GSE232159_Deseq2_USA300_1h_vs_Ctrl_1h.txt.gz |
5.3 Mb |
(ftp)(http) |
TXT |
| GSE232159_Deseq2_USA300_6h_vs_Ctrl_6h.txt.gz |
5.3 Mb |
(ftp)(http) |
TXT |
| GSE232159_Raw_read_counts_All.txt.gz |
1.6 Mb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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