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| Status |
Public on Apr 05, 2024 |
| Title |
The cellular landscape of the healthy human intervertebral disc: identification of new immature cell populations and their relationship with mature populations at single cell resolution |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
For this study, we applied scRNA-seq to cells from surgically separated annulus fibrosus and nucleus pulposus tissues to identify A) thecellular landscapes of healthytissues, and B) characterize in detail the composition andgene regulatory networksof immature cell populations.
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| Overall design |
Single cell level analysis of annulus fibrosus and nucleus pulposus tissues from human healthy (n=3, n=3) intervertebral discs (IVDs).
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| Contributor(s) |
Mertens J, Swahn H, Olmer M, Myers K, Mondala TS, Natarajan P, Head SR, Alvarez-Garcia O, Lotz MK |
| Citation(s) |
38403470 |
| |
| Submission date |
Apr 14, 2023 |
| Last update date |
Apr 06, 2024 |
| Contact name |
Padma Natarajan |
| E-mail(s) |
ccbb@scripps.edu
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| Organization name |
The Scripps Research Institute
|
| Department |
CCBB
|
| Street address |
10550 N.Torrey Pines Road
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| City |
La Jolla |
| State/province |
CA |
| ZIP/Postal code |
92037 |
| Country |
USA |
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| Platforms (1) |
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| Samples (6)
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| GSM7173748 |
healthy annulus fibrosus (Thompson grade II) single cell RNAseq, donor1 |
| GSM7173749 |
healthy annulus fibrosus (Thompson grade II) single cell RNAseq, donor2 |
| GSM7173750 |
healthy annulus fibrosus (Thompson grade II) single cell RNAseq, donor3 |
| GSM7173751 |
healthy nucleus pulposus (Thompson grade II) single cell RNAseq, donor1 |
| GSM7173752 |
healthy nucleus pulposus (Thompson grade II) single cell RNAseq, donor2 |
| GSM7173753 |
healthy nucleus pulposus (Thompson grade II) single cell RNAseq, donor3 |
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| This SubSeries is part of SuperSeries: |
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| Relations |
| BioProject |
PRJNA955672 |
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