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| Status |
Public on Aug 25, 2023 |
| Title |
Lowering dietary BCAA reduces fibrosis, enhances mitochondrial respiration, and curbs cardiac hypertrophy, via regulating histone H3K23-propionylation |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
This SuperSeries is composed of the SubSeries listed below.
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| Overall design |
Refer to individual Series
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| Web link |
https://pubmed.ncbi.nlm.nih.gov/37669116/
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| Citation(s) |
37669116 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R01 HL146537 |
Transcriptional mechanisms in cardiac hypertrophy |
RUTGERS BIOMEDICAL AND HEALTH SCIENCES |
Maha Abdellatif |
| R01 HL157739 |
The regulation of the histone code during cardiac hypertrophy |
RUTGERS BIOMEDICAL AND HEALTH SCIENCES |
Maha Abdellatif |
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| Submission date |
Apr 06, 2023 |
| Last update date |
Nov 25, 2023 |
| Contact name |
Maha Abdellatif |
| E-mail(s) |
abdellma@rutgers.edu
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| Phone |
9739721254
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| Organization name |
Rutgers University
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| Department |
Cell Biology and Molecular Medicine
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| Street address |
185 S. Orange Ave., MSB
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| City |
Newark |
| State/province |
NJ |
| ZIP/Postal code |
07103 |
| Country |
USA |
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| Platforms (3) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (50)
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| GSM7091776 |
BCAA-control, TAC, rep1 [BCT1] |
| GSM7091777 |
BCAA-control, TAC, rep2 [BCT2] |
| GSM7091778 |
BCAA-control, TAC, rep3 [BCT3] |
| GSM7091779 |
BCAA-free, sham, rep1 [BFS1] |
| GSM7091780 |
BCAA-free, sham, rep2 [BFS2] |
| GSM7091781 |
BCAA-free, sham, rep3 [BFS3] |
| GSM7091782 |
BCAA-free, TAC, rep1 [BFT1] |
| GSM7091783 |
BCAA-free, TAC, rep2 [BFT2] |
| GSM7091784 |
BCAA-free, TAC, rep3 [BFT3] |
| GSM7093475 |
BCAA-control-prop, sham, rep1 |
| GSM7093476 |
BCAA-control-prop, sham, rep2 |
| GSM7093477 |
BCAA-control-prop, sham, rep3 |
| GSM7093478 |
BCAA-control-prop, TAC, rep1 |
| GSM7093479 |
BCAA-control-prop, TAC, rep2 |
| GSM7093480 |
BCAA-control-prop, TAC, rep3 |
| GSM7093481 |
BCAA-free-prop, sham, rep1 |
| GSM7093482 |
BCAA-free-prop, sham, rep2 |
| GSM7093483 |
BCAA-free-prop, sham, rep3 |
| GSM7093484 |
BCAA-free-prop, TAC, rep1 |
| GSM7093485 |
BCAA-free-prop, TAC, rep2 |
| GSM7093486 |
BCAA-free-prop, TAC, rep3 |
| GSM7093487 |
BCAA-control w prop, sham [Sham-control-prop_H3K23Pr] |
| GSM7093488 |
BCAA-control w prop, TAC [TAC-control-prop_H3K23Pr] |
| GSM7093489 |
BCAA-free w prop, sham [Sham-0BCAA-prop_H3K23Pr] |
| GSM7093490 |
BCAA-free w prop,TAC [TAC-0BCAA-prop_H3K23Pr] |
| GSM7093491 |
pooled-input [Pooled_Input] |
| GSM7093492 |
BCAA-control, sham [Sham-b-Cont-H3K23Pr] |
| GSM7093493 |
BCAA-control, TAC [TAC-b-Cont-H3K23Pr] |
| GSM7093494 |
BCAA-free, sham [Sham-BCAA-H3K23Pr] |
| GSM7093495 |
BCAA-free,TAC [TAC-BCAA-H3K23Pr] |
| GSM7093496 |
heart, BCAA-control, sham [1_Sham-2W_H3K23Pr] |
| GSM7093497 |
heart, BCAA-control, TAC [2_TAC-2W_H3K23Pr] |
| GSM7093498 |
heart, BCAA-free, sham [3_Sham-0BCAA-2W_H3K23Pr] |
| GSM7093499 |
heart, BCAA-free, TAC [4_TAC-0BCAA-2W_H3K23Pr] |
| GSM7093500 |
heart, sham, TAC, pooled [5_Pooled_Input] |
| GSM7152995 |
BCAA-control, 2W-sham, rep1 |
| GSM7152996 |
BCAA-control, 2W-sham, rep2 |
| GSM7152997 |
BCAA-control, 2W-sham, rep3 |
| GSM7152998 |
BCAA-control, 2W-TAC, rep1 |
| GSM7152999 |
BCAA-control, 2W-TAC, rep2 |
| GSM7153000 |
BCAA-control, 2W-TAC, rep3 |
| GSM7153001 |
BCAA-free, 2W-sham, rep1 |
| GSM7153002 |
BCAA-free, 2W-sham, rep2 |
| GSM7153003 |
BCAA-free, 2W-sham, rep3 |
| GSM7153004 |
BCAA-free, 2W-TAC, rep1 |
| GSM7153005 |
BCAA-free, 2W-TAC, rep2 |
| GSM7153006 |
BCAA-free, 2W-TAC, rep3 |
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| This SuperSeries is composed of the following SubSeries:
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| GSE227110 |
The effect of a BCCA-free diet on 1W pressure overload-induced cardiac gene expression |
| GSE227225 |
The effect of a BCCA-free diet, with 1% propionate, on 1W pressure overload-induced cardiac gene expression [BCAA-free w propionate-1W-TAC-RNA-Seq] |
| GSE227226 |
The effect of a BCCA-free, with 1% propionate, diet on 1W pressure overload-induced H3K23-propionyl [BCAA-free-1W-TAC with propionate-ChIP-Seq] |
| GSE227227 |
The effect of a BCCA-free diet on 1W pressure overload-induced H3K23-propionyl [BCAA-free-1W-TAC-ChIP-Seq] |
| GSE227228 |
The effect of a BCCA-free diet on 2W pressure overload-induced H3K23-propionyl [BCAA-free-2W-TAC-ChIP-Seq] |
| GSE229128 |
The effect of a BCCA-free diet on 2W pressure overload-induced cardiac gene expression [BCAA-free-2W-TAC-RNA-Seq] |
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| Relations |
| BioProject |
PRJNA953006 |
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