|
| Status |
Public on Mar 03, 2023 |
| Title |
Gene expression of small peritoneal macrophages (SPM) |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Transcriptome of SPM (small peritoneal macrophages) from mice infected with LPS and treated with LCC-12
|
| |
|
| Overall design |
Experiments were performed on 5-week-old male SWISS mice. Male littermates were randomly assigned to experimental groups. The experimental endotoxemic model was induced by intraperitoneal (IP) injection of LPS (20 mg/kg) )(Escherichia coli O55:B5, Sigma-Aldrich, L2880). All the animals were resuscitated with 30 mL/kg body weight of saline administered subcutaneously 6 h post LPS administration. Mice were intra-peritoneally injected with LCC-12 (0.3 mg/kg 6 h after LPS challenge). Mice were sacrificed 22 h post-LPS challenge.
|
| |
|
| Contributor(s) |
Solier S, Muller S, Caneque T, Versini A, Gestraud P, Trotten F, Servant N, Watson S, Rodriguez R |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jan 20, 2023 |
| Last update date |
Mar 03, 2023 |
| Contact name |
Nicolas Servant |
| E-mail(s) |
Nicolas.Servant@curie.fr
|
| Organization name |
Institut Curie
|
| Street address |
26 rue d'ulm
|
| City |
Paris Cedex 05 |
| ZIP/Postal code |
75248 |
| Country |
France |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (2) |
|
| This SubSeries is part of SuperSeries: |
| GSE160864 |
Discovery of a druggable copper-signaling pathway that drives inflammation |
|
| Relations |
| BioProject |
PRJNA925915 |
