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Status |
Public on Feb 10, 2023 |
Title |
ATAC-Seq analysis of the chromatin accessibilities in C9HRE ALS/FTD patient cells |
Organism |
Homo sapiens |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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Summary |
ATAC-seq was utilized to profile the chromatin status in ALS/FTD patient cells carrying the hexanuleotide repeat expansion in C9orf72.
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Overall design |
ATAC-seq was performed on control and C9orf72 HRE B lymphocytes and iPSCs-derived motor neurons.
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Contributor(s) |
Liu Y, Liu H, Wang J |
Citation(s) |
36822200 |
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Submission date |
Jan 19, 2023 |
Last update date |
May 12, 2023 |
Contact name |
Yang Liu |
E-mail(s) |
liuyang19870210@outlook.com
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Organization name |
Johns Hopkins University
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Department |
Biochemistry and Molecular Biology
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Lab |
Wang Lab
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Street address |
615 N. Wolfe Street
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City |
Baltimore |
State/province |
MD |
ZIP/Postal code |
21211 |
Country |
USA |
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Platforms (1) |
GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
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Samples (6)
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GSM6944027 |
ATAC-seq for B lymphocytes from a healthy people |
GSM6944028 |
ATAC-seq for C9HRE B lymphocytes from a ALS/FTD patient |
GSM6944029 |
ATAC-seq for iPSCs-derived motor neurons from a healthy people_1 |
GSM6944030 |
ATAC-seq for iPSCs-derived motor neurons from a healthy people_2 |
GSM6944031 |
ATAC-seq for iPSCs-derived motor neurons from a ALS/FTD patient carrying the C9orf72 HRE mutation_1 |
GSM6944032 |
ATAC-seq for iPSCs-derived motor neurons from a ALS/FTD patient carrying the C9orf72 HRE mutation_2 |
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This SubSeries is part of SuperSeries: |
GSE223259 |
Chromatin accessibilities in C9HRE ALS/FTD patient cells |
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Relations |
BioProject |
PRJNA925663 |