|
| Status |
Public on Nov 27, 2023 |
| Title |
RNA sequencing of human pancreatic acinar and ductal cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Flow-sorted pancreatic acinar and ductal cells from fresh human pancreatic exocrine tissue were subjected to molecular characterization to identify lineage-specific expression and epigenetic properties. Cells of both lineages were cultured and transformed via lentiviral mutation to form pancreatic ductal adenocarcinoma.
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| |
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| Overall design |
Flow-sorted pancreatic acinar and ductal cells from fresh human pancreatic exocrine tissue were subjected to RNAseq, before and after cell culture, for differential analysis of gene expression by lineage, condition, and genotype.
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| |
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| Contributor(s) |
Xu Y, Nipper MH, Ye Z, Akanuma N, Lopez K, Deng JJ, Singhi AD, Sharkey FE, Wang H, Sun L, Chen Y, Liu J, Wang P |
| Citation(s) |
38247878, 38280869 |
| |
| Submission date |
Jan 16, 2023 |
| Last update date |
Feb 14, 2024 |
| Contact name |
Pei Wang |
| E-mail(s) |
wangp3@uthscsa.edu
|
| Organization name |
University of Texas Health San Antonio
|
| Department |
Cell Systems & Anatomy
|
| Street address |
7703 Floyd Curl Dr
|
| City |
San Antonio |
| State/province |
TX |
| ZIP/Postal code |
78229 |
| Country |
USA |
| |
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| Platforms (2) |
| GPL21290 |
Illumina HiSeq 3000 (Homo sapiens) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (28)
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| This SubSeries is part of SuperSeries: |
| GSE222991 |
Functional Genomics of human pancreatic acinar and ductal cells |
|
| Relations |
| BioProject |
PRJNA924346 |
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