GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE22288 Query DataSets for GSE22288
Status Public on May 13, 2011
Title Controlled ErbB receptor dimerization
Organism Homo sapiens
Experiment type Expression profiling by array
Summary In order to better understand signaling events following receptor dimerization involving HER2, we have generated an experimental system in which ErbB dimerization can be controlled.
We used gene expression microarrays to identify genes and pathways that are differentially activated by HER2 homodimers and HER2 containing heterodimers.
Overall design MCF10A-HER2-FKBP-HA cells were treated with AP1510, TGFalpha or heregulin for 48 hrs prior to RNA harvest for array analysis.
Contributor(s) Ghosh R, Arteaga CL, Balko JM
Citation(s) 21324925
Submission date Jun 10, 2010
Last update date Jul 26, 2018
Contact name Ritwik Ghosh
Organization name Vanderbilt University
Street address 2220 Pierce Avenue, 777 PRB
City Nashville
State/province TN
ZIP/Postal code 37232
Country USA
Platforms (1)
GPL6244 [HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Samples (12)
GSM554579 Untreated 979-CLA-25
GSM554580 Untreated 979-CLA-26
GSM554581 Untreated 979-CLA-27
BioProject PRJNA127399

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE22288_RAW.tar 50.0 Mb (http)(custom) TAR (of CEL, CHP)
Raw data provided as supplementary file
Processed data included within Sample table
Processed data provided as supplementary file

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap