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Series GSE22131 Query DataSets for GSE22131
Status Public on Jul 08, 2010
Title High resolution analysis of genomic imprinting in the embryonic and adult mouse brain AND Sex-specific imprinting in the mouse brain
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Genomic imprinting results in the preferential expression of the paternal, or maternal allele of certain genes. We have performed a genome-wide characterization of imprinting in the mouse embryonic and adult brain using F1 hybrid mice generated from reciprocal crosses of CASTEiJ and C57BL/6J mice. We also uncovered genes associated with sex specific parental effects in the adult mouse brain. Our study identified preferential selection of the maternally inherited X chromosome in glutamatergic neurons of the female cortex.
 
Overall design Examination of allele specific expression in the brains of reciprocal crosses of F1 hybrid mice from CASTEiJ and C57BL/6J crosses.

Processed data files (GenomicAligned, SNP_calls, TranscriptomeAligned, fRNAdbAligned) and README file linked below as supplementary files.
 
Contributor(s) Gregg C, Dulac C
Citation(s) 20616232, 22019781, 20616234
Submission date Jun 04, 2010
Last update date May 15, 2019
Contact name Catherine Dulac
E-mail(s) dulac@fas.harvard.edu
Organization name Harvard University
Department Molecular and Cellular Biology
Street address BL4017 16 Divinity Ave
City Cambridge
State/province MA
ZIP/Postal code 02138
Country USA
 
Platforms (1)
GPL9250 Illumina Genome Analyzer II (Mus musculus)
Samples (32)
GSM563763 E15_CastEiJ_RNASeq_techrep1
GSM563764 E15_C57BL/6J_RNASeq_techrep1
GSM563765 E15_CastEiJ_RNASeq_techrep2
Relations
SRA SRP002811
BioProject PRJNA127583

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE22131_E15_GenomicAligned.csv.gz 2.5 Mb (ftp)(http) CSV
GSE22131_E15_SNP_calls.txt.gz 1.5 Mb (ftp)(http) TXT
GSE22131_E15_TranscriptomeAligned.csv.gz 3.8 Mb (ftp)(http) CSV
GSE22131_E15_fRNAdbAligned.csv.gz 1.6 Mb (ftp)(http) CSV
GSE22131_PFC_GenomicAligned.csv.gz 1.6 Mb (ftp)(http) CSV
GSE22131_PFC_SNP_calls.txt.gz 1.5 Mb (ftp)(http) TXT
GSE22131_PFC_TranscriptomeAligned.csv.gz 2.4 Mb (ftp)(http) CSV
GSE22131_PFC_fRNAdbAligned.csv.gz 1.0 Mb (ftp)(http) CSV
GSE22131_POA_GenomicAligned.csv.gz 1.7 Mb (ftp)(http) CSV
GSE22131_POA_SNP_calls.txt.gz 1.5 Mb (ftp)(http) TXT
GSE22131_POA_TranscriptomeAligned.csv.gz 2.6 Mb (ftp)(http) CSV
GSE22131_POA_fRNAdbAligned.csv.gz 1.0 Mb (ftp)(http) CSV
GSE22131_ProcessedDataFiles_README.txt 2.3 Kb (ftp)(http) TXT
SRA Run SelectorHelp
Processed data are available on Series record
Raw data are available in SRA
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