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Series GSE21900 Query DataSets for GSE21900
Status Public on May 18, 2011
Title Expression profiling of the Otx2 CKO retina
Organism Mus musculus
Experiment type Expression profiling by array
Summary In the vertebrate retina, the Otx2 transcription factor plays a crucial role in the cell fate determination of both rod and cone photoreceptors. Otx2 conditional knockout (CKO) mice exhibited a total absence of rods and cones in the retina due to their cell fate conversion to amacrine-like cells. In order to investigate the entire transcriptome regulated by Otx2 in the developing retina, we performed microarray analysis on the Otx2 CKO retina.
Overall design In order to clarify the molecular role of Otx2 in transcriptional regulation during development, we investigated the expression profile of the Otx2 CKO retina compared with that of the control retina with the genotype Otx2flox/flox;Crx-cre- using microarrays at two time points, P1 and P12.
Contributor(s) Omori Y, Sato S, Furukawa T
Citation(s) 21602925
Submission date May 19, 2010
Last update date Feb 11, 2019
Contact name Takahisa Furukawa
Organization name Osaka Bioscience Institute
Department Developmental Biology
Lab Furukawa Lab
Street address 6-2-4 Furuedai
City Suita
State/province Osaka
ZIP/Postal code 565-0874
Country Japan
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (12)
GSM544741 P1-control-ex1
GSM544742 P1-control-ex2
GSM544743 P1-control-ex3
BioProject PRJNA126863

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE21900_RAW.tar 52.2 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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