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Series GSE21863 Query DataSets for GSE21863
Status Public on Sep 12, 2011
Title Transcriptome of the Nxnl2-/- mouse retina
Organism Mus musculus
Experiment type Expression profiling by array
Summary A nxnl2 knockout mouse model was created and the transcriptome used to demonstrate that the retina is compromised by the absence of nxnl2.
For the mouse lacking Nxnl2, the gene encoding RdCVF2, the progressive decline of the visual performance of the cones in parallel with their degeneration arises due to loss of trophic support from RdCVF2

Keywords: genetic modification, transcription-profile, retina
Overall design In total 6 samples were analyzed, they represent the genotypes wt/wt and ko/ko that were tested in triplicate each.
Contributor(s) Jaillard C, Mouret A, Niepon M, Irene L, Emanuelle C, Aït-Ali N, Millet-Puel G, Sedmak T, Yang Y, Raffelsberger W, Kinzel B, Trembleau A, Poch O, Bennett J, Wolfrum U, Lledo M, Sahel J, Leveillard T
Citation(s) 22343139
Submission date May 17, 2010
Last update date Feb 11, 2019
Contact name Wolfgang Raffelsberger
Organization name IGBMC
Department DBGS
Street address 1 rue Laurent Fries
City Illkirch/Strasbourg
ZIP/Postal code 67404
Country France
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (6)
GSM543809 retina_wt/wt_rep1
GSM543810 retina_wt/wt_rep2
GSM543811 retina_wt/wt_rep3
BioProject PRJNA127047

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE21863_RAW.tar 35.6 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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