 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on Jul 07, 2023 |
| Title |
Study of the changes on MAIT cell transcriptome after exposure to Klebsiella pneumoniae, interferon alpha and influenza virus |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To investigate the molecular mechanisms mediating activation of human circulating MAIT cells during infection with Klebsiella pneumoniae and compare the transcriptomics with cells activated by type-I interferons or influenza virus
|
| |
|
| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for human circulating MAIT cells after exposure to 3 conditions: Klebsiella pneumoniae, IFNα2A and influenza virus
|
| |
|
| Contributor(s) |
Lopez-Rodriguez JC, Barrington C, Barral P |
| Citation(s) |
37516912 |
| |
| Submission date |
Nov 22, 2022 |
| Last update date |
Oct 06, 2023 |
| Contact name |
Patricia Barral |
| E-mail(s) |
patricia.barral@kcl.ac.uk
|
| Organization name |
King's College London
|
| Street address |
London
|
| City |
London |
| ZIP/Postal code |
SE19RT |
| Country |
United Kingdom |
| |
|
| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (16)
|
| GSM6753121 |
MAIT cells, Healthy donor 1, Influenza virus |
| GSM6753122 |
MAIT cells, Healthy donor 2, Control |
| GSM6753123 |
MAIT cells, Healthy donor 2, Klebsiella |
| GSM6753124 |
MAIT cells, Healthy donor 2, IFNα2A |
| GSM6753125 |
MAIT cells, Healthy donor 2, Influenza virus |
| GSM6753126 |
MAIT cells, Healthy donor 3, Control |
| GSM6753127 |
MAIT cells, Healthy donor 3, Klebsiella |
| GSM6753128 |
MAIT cells, Healthy donor 3, IFNα2A |
| GSM6753129 |
MAIT cells, Healthy donor 3, Influenza virus |
| GSM6753130 |
MAIT cells, Healthy donor 4, Control |
| GSM6753131 |
MAIT cells, Healthy donor 4, Klebsiella |
| GSM6753132 |
MAIT cells, Healthy donor 4, IFNα2A |
| GSM6753133 |
MAIT cells, Healthy donor 4, Influenza virus |
|
| Relations |
| BioProject |
PRJNA904387 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE218601_RAW.tar |
22.1 Mb |
(http)(custom) |
TAR (of RESULTS) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
|
|
|
|
 |
Less...
More...