|
| Status |
Public on Jan 29, 2023 |
| Title |
Spatial epigenome-transcriptome co-profiling of mammalian tissues |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We present spatially resolved high-spatial-resolution genome-wide co-mapping of epigenome and transcriptome by simultaneously profiling of chromatin accessibility and gene expression (spatial-ATAC-RNA-seq), as well as histone modification and gene expression (spatial-CUT&Tag-RNA-seq) on the same tissue section at cellular level by combining the microfluidic deterministic barcoding strategy in DBiT-seq and the chemistry used in ATAC-seq/CUT&Tag.
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| |
|
| Overall design |
Spatially resolved co-sequencing of epigenome and transcriptome in mouse embryos and mouse brains.
|
| |
|
| Contributor(s) |
Fan R, Zhang D |
| Citation(s) |
36922587 |
| |
| Submission date |
Nov 22, 2022 |
| Last update date |
Apr 14, 2023 |
| Contact name |
Di Zhang |
| E-mail(s) |
di.zhang@yale.edu
|
| Organization name |
Yale University
|
| Department |
Biomedical Engineering
|
| Street address |
55 Prospect St
|
| City |
New Haven |
| State/province |
CT |
| ZIP/Postal code |
06511 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE205055 |
Spatial epigenome-transcriptome co-profiling of mammalian tissues |
|
| Relations |
| BioProject |
PRJNA904377 |
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