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| Status |
Public on Sep 30, 2023 |
| Title |
PAX3-FOXO1 drives tumor formation from multiple lineages [scRNA-seq] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Comparison of fusion-positive rhabdomyosarcoma tumors from endothelial and myogenic origins to wild-type tissue shows few differences between the two tumors.
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| |
|
| Overall design |
We performed single cell gene expression profiling analysis fo scRNA-seq data for multiple endothelial cell types and two genetically engineered mouse models of rhabdomyosarcoma.
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| |
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| Contributor(s) |
Searcy MB, Jin H, Hatley ME |
| Citation(s) |
37968277 |
| |
| Submission date |
Nov 18, 2022 |
| Last update date |
Jan 03, 2024 |
| Contact name |
Hongjian Jin |
| E-mail(s) |
hongjian.jin@STJUDE.ORG
|
| Organization name |
St Jude Children's Research Hospital
|
| Department |
Center for Applied Bioinformatics
|
| Street address |
262 Danny Thomas Place
|
| City |
Memphis |
| State/province |
TN |
| ZIP/Postal code |
38015 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (13)
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| This SubSeries is part of SuperSeries: |
| GSE218274 |
PAX3-FOXO1 expression in endothelial progenitors dictates myogenic reprogramming and rhabdomyosarcoma identity |
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| Relations |
| BioProject |
PRJNA903207 |
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