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| Status |
Public on Dec 31, 2022 |
| Title |
Akkermansia muciniphila blunts Th17 cells [Colonic lymphocytes] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
DSS-induced colitis mice were treated with PBS, A. muciniphila secreting extracellular vesicles (SEV) via gavage every day. Mice lymphocytes of colon tissues from each of the indicated group (Colitis and SEV) in were collected. Then CD4+ T cells are isolated from lymphocytes. These cells were submitted for scRNA-seq.
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| Overall design |
Seven mice colon tissues from each of the indicated group (Colitis and SEV) were collected. Lymphocytes of three or four colon tissues from each group were mixed equally as one sample and submitted for scRNA-seq.
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| Contributor(s) |
Xu Y, Zheng C, Jiang Y, Zhang M |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Sep 27, 2022 |
| Last update date |
Jan 02, 2023 |
| Contact name |
Mingming Zhang |
| E-mail(s) |
zhangchimei@126.com
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| Phone |
18551831115
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| Organization name |
Shanghai Jiao Tong University School of Medicine
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| Street address |
145 Middle Shandong Road
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| City |
Shanghai |
| ZIP/Postal code |
200001 |
| Country |
China |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA884634 |
