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| Status |
Public on Jul 08, 2025 |
| Title |
Mutation of ATRX induces type I interferon signalling and defines a non-canonical role of nuclear cGAS in the regulation of chromatin state |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
Expression profiling by high throughput sequencing
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| Summary |
This SuperSeries is composed of the SubSeries listed below.
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| Overall design |
Refer to individual Series
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| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Sep 08, 2022 |
| Last update date |
Jul 08, 2025 |
| Contact name |
Graeme Grimes |
| E-mail(s) |
graeme.grimes@ed.ac.uk
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| Phone |
07769115077
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| Organization name |
University of Edinburgh
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| Street address |
MRC Institute of Genetics & Molecular Medicine, Crewe Road,
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| City |
Edinburgh |
| ZIP/Postal code |
EH4 2XU |
| Country |
United Kingdom |
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| Platforms (1) |
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| Samples (20)
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| GSM6561130 |
iPSC-KI, Rep1 |
| GSM6561131 |
iPSC-KI, Rep2 |
| GSM6561132 |
iPSC-KI, Rep3 |
| GSM6561133 |
NPC-WT, Rep1 |
| GSM6561134 |
NPC-WT, Rep2 |
| GSM6561135 |
NPC-WT, Rep3 |
| GSM6561136 |
NPC-KI, Rep1 |
| GSM6561137 |
NPC-KI, Rep2 |
| GSM6561138 |
NPC-KI, Rep3 |
| GSM6561139 |
Neuron-WT, Rep1 |
| GSM6561140 |
Neuron-WT, Rep2 |
| GSM6561141 |
Neuron-WT, Rep3 |
| GSM6561142 |
Neuron-WT, Rep4 |
| GSM6561143 |
Neuron-KI, Rep1 |
| GSM6561144 |
Neuron-KI, Rep2 |
| GSM6561145 |
Neuron-KI, Rep3 |
| GSM6561146 |
Neuron-KI, Rep4 |
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| This SuperSeries is composed of the following SubSeries: |
| GSE212922 |
Differential gene expression analysis at different stages of neuronal development in mutant and wild type ATRX cells |
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| Relations |
| BioProject |
PRJNA878466 |
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