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| Status |
Public on Nov 02, 2023 |
| Title |
Transcriptional dysregulation impairs efficacy of neural stem cell activation during aging [scRNA-seq] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To gain insight of the decreasing activation efficacy in the aging NSCs, we performed single-cell transcriptomics analysis using the Chromium Single Cell 3’ platform (10x Genomics).
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| Overall design |
Primary NSCs were isolated from the subventricular zone of the lateral ventricles (SVZ) in the brains of the young and aged mice, repectively. The isolated cells were used in scRNAseq analysis.
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| Contributor(s) |
Li M, Huang C |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Sep 05, 2022 |
| Last update date |
Nov 02, 2023 |
| Contact name |
Chengyang Peter Huang |
| E-mail(s) |
chengyhuang@hotmail.com
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| Organization name |
Shantou University Medical College
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| Street address |
22 Xinling Street
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| City |
Shantou |
| ZIP/Postal code |
515041 |
| Country |
China |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (2) |
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| This SubSeries is part of SuperSeries: |
| GSE212725 |
Transcriptional and epigenetic dysregulation impairs generation of proliferative neural stem and progenitor cells during brain aging |
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| Relations |
| BioProject |
PRJNA877033 |
