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| Status |
Public on Mar 29, 2023 |
| Title |
Direct reprogramming of human fibroblasts towards beta-like cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We reprogrammed human foreskin fibroblasts towards beta-like cells via adenovirus-mediated sequential introduction of five transcription factors (Ngn3, Pdx1, Mafa. pax4, Nkx2-2). At day 11 after initial viral infection, we isolated RNA and performed gene expression profiling analysis using data obtained from RNA-seq of 3 parental fibroblasts and 3 reprogrammed cell samples (corresponding to 3 independent reprogramming experiments)
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| |
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for fibroblasts and reprogrammed beta-like cells.
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| |
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| Contributor(s) |
Gasa R, Fontcuberta-Pisunyer M |
| Citation(s) |
36964318 |
| |
| Submission date |
Jul 29, 2022 |
| Last update date |
Mar 30, 2023 |
| Contact name |
Rosa Gasa |
| E-mail(s) |
rgasa@recerca.clinic.cat
|
| Phone |
+34 661649269
|
| Organization name |
IDIBAPS
|
| Street address |
C/Rosselló 149-153
|
| City |
Barcelona |
| ZIP/Postal code |
08036 |
| Country |
Spain |
| |
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| Platforms (1) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA863613 |
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