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| Status |
Public on Apr 01, 2024 |
| Title |
Transcriptional Activation of Regenerative Haematopoiesis via Niche Sensing [snRNA/ATACseq HSPC Multiome] |
| Organism |
Mus |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
Multiome single nuclei RNA/ATAC-seq analysis was performed on sorted population of SLAM LSK HSPCs to uncover transcriptional determinants regulating HSPCs in distinct transitional states.
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| Overall design |
SLAM LSK HSPCs were harvested isolated and sorted from flushed and crushed murine tibias and femurs. SLAM LSK HSPCs pooled from 20 mice were analyzed by multiome 10X sequencing procedure.
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| Contributor(s) |
Itkin T, Houghton S, Rafii S |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jul 12, 2022 |
| Last update date |
Apr 01, 2024 |
| Contact name |
Tomer Itkin |
| E-mail(s) |
toi2003@med.cornell.edu
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| Organization name |
Weill Cornell Medicine
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| Department |
Medicine
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| Lab |
Rafii
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| Street address |
1300 York Avenue, A-869
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| City |
NY |
| State/province |
NY |
| ZIP/Postal code |
10065 |
| Country |
USA |
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| Platforms (1) |
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| Samples (2) |
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| This SubSeries is part of SuperSeries: |
| GSE169431 |
Transcriptional Activation of Regenerative Haematopoiesis via Niche Sensing |
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| Relations |
| BioProject |
PRJNA858048 |
