|
| Status |
Public on Jun 27, 2022 |
| Title |
Splice Factor Polypyrimidine tract-binding protein 1 (Ptbp1) Primes Endothelial Inflammation in Atherogenic Disturbed Flow Conditions [CRISPR] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Analysis of effects of Ptbp1 deletion on RNA splicing and expression in aortic endothelial cells
|
| |
|
| Overall design |
A mouse aortic endothelial cell line with CRISPR deletion (single cell clone) of Ptbp1, and then rescue with human PTBP1 cDNA was analyzed before and after TNF treatment.
|
| |
|
| Contributor(s) |
Murphy P, Hensel J |
| Citation(s) |
35858420 |
| |
| Submission date |
Jun 24, 2022 |
| Last update date |
Aug 02, 2022 |
| Contact name |
Patrick A Murphy |
| E-mail(s) |
pamurphy@uchc.edu
|
| Organization name |
University of Connecticut Health Center
|
| Department |
Center for Vascular Biology
|
| Lab |
Murphy
|
| Street address |
263 Farmington Ave
|
| City |
Farmington |
| State/province |
CT |
| ZIP/Postal code |
06030 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (6)
|
|
| This SubSeries is part of SuperSeries: |
| GSE206851 |
Splice Factor Polypyrimidine tract-binding protein 1 (Ptbp1) Primes Endothelial Inflammation in Atherogenic Disturbed Flow Conditions |
|
| Relations |
| BioProject |
PRJNA852426 |
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