|
| Status |
Public on May 31, 2023 |
| Title |
m6A-sequencing of Mettl14-conditional knock-out retinas and matched control. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Other
|
| Summary |
Post-transcriptional m6A methylation on mRNA plays a key role in neural development. Here, we specifically depleted Mettl14 (a key component of m6A complex) in retina progenitor cells by crossing Mettl14 fl/fl mice with the Chx10-Egfp/Cre mouse line and investigated Mettl14 depletion-induced m6A alteration in developing retinas using m6A-seq.
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| |
|
| Overall design |
Immunoprecipitation of m6A-enriched mRNAs (m6A-seq) for control and Mettl14 cKO retinas.
|
| Web link |
http://DOI: 10.1016/j.celrep.2023.112596
|
| |
|
| Contributor(s) |
Liang L, Wang S |
| Citation(s) |
37269288 |
| |
| Submission date |
Jun 13, 2022 |
| Last update date |
Aug 31, 2023 |
| Contact name |
Yue Sun |
| E-mail(s) |
sunyue@stanford.edu
|
| Organization name |
Stanford University
|
| Street address |
290 Jane Stanford Way
|
| City |
Stanford |
| State/province |
CA |
| ZIP/Postal code |
94305 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA848799 |
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