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| Status |
Public on Sep 20, 2022 |
| Title |
Abnormal Transcriptome-wide of DNA demethylation in Folate deficiency caused neural tube defects [MeDIP] |
| Organism |
Mus musculus |
| Experiment type |
Methylation profiling by high throughput sequencing
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| Summary |
To investigate the associated with abnormal DNA demethylation and neural tube defects (NTDs) with folate deficiency, we etablished mouse embryonic stem cells (mESCs) Sv/129 in folate-deficiency-treated.
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| Overall design |
We then performed 5mC profiling analysis using data obtained from MeDIP-seq of the cell model.
Comparative 5mC profiling analysis of RNA-seq data for sv129 cells as control group and its folate-deficiency-treated as experimental group.
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| Contributor(s) |
Wang S, Zeng Y, Pei P, Zhang T |
| Citation missing |
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| Submission date |
May 26, 2022 |
| Last update date |
Sep 21, 2022 |
| Contact name |
shan wang |
| E-mail(s) |
wsaquarius@sina.com
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| Organization name |
Capital Institute of Pediatrics
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| Street address |
2yabao road
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| City |
beijing |
| ZIP/Postal code |
100020 |
| Country |
China |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (3) |
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| This SubSeries is part of SuperSeries: |
| GSE204874 |
Abnormal Transcriptome-wide of DNA demethylation in Folate deficiency caused neural tube defects |
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| Relations |
| BioProject |
PRJNA842657 |
