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| Status |
Public on May 18, 2022 |
| Title |
Identification of DDX3X-dependent translation targets in the E11.5 mouse cortex |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Other
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| Summary |
To identify DDX3X-dependent translation targets in the developing mouse cortex, we used E11.5 cortices from both sexes of wildtype and conditional Ddx3x knockout mice (driven by Emx1-Cre). We performed RNAseq and Riboseq on these samples in parallel.
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq and Ribo-seq data for wildtype and Ddx3x conditional knockout mouse E11.5 cortex. The following are biological replicates: Female controls: F2, F3; Male controls: M1, M2, M3; cKO females: F1, F2, F3; cKO mals: M1, M2, M3
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| Contributor(s) |
Hoye M, Calviello L, Silver D |
| Citation(s) |
35762573, 38273160 |
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| Submission date |
May 16, 2022 |
| Last update date |
Mar 13, 2024 |
| Contact name |
Debra Silver |
| E-mail(s) |
debra.silver@duke.edu
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| Phone |
919-668-7909
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| Organization name |
Duke University School of Medicine
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| Department |
Molecular Genetics and Microbiology
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| Street address |
224 CARL Building
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| City |
Durham |
| State/province |
North Carolina |
| ZIP/Postal code |
27710 |
| Country |
USA |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (22)
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| GSM6153495 |
CKO male1, RNAseq |
| GSM6153496 |
CKO male2, RNAseq |
| GSM6153497 |
CKO male3, RNAseq |
| GSM6153498 |
control female2, RNAseq |
| GSM6153499 |
control female3, RNAseq |
| GSM6153500 |
control male1, RNAseq |
| GSM6153501 |
control male2 RNAseq |
| GSM6153502 |
control male3 RNAseq |
| GSM6153503 |
CKO female1, Riboseq |
| GSM6153504 |
CKO female2, Riboseq |
| GSM6153505 |
CKO female3 Riboseq |
| GSM6153506 |
CKO male1, Riboseq |
| GSM6153507 |
CKO male2, Riboseq |
| GSM6153508 |
CKO male3, Riboseq |
| GSM6153509 |
control female2, Riboseq |
| GSM6153510 |
control female3, Riboseq |
| GSM6153511 |
control male1, Riboseq |
| GSM6153512 |
control male2, Riboseq |
| GSM6153513 |
control male3, Riboseq |
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| Relations |
| BioProject |
PRJNA838490 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE203078_Supplemental_File_3.xlsx |
3.9 Mb |
(ftp)(http) |
XLSX |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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