|
| Status |
Public on May 13, 2022 |
| Title |
Identification of antimalarial compounds that inhibit Apicomplexan AP2 transcription factor proteins in the human malaria parasite Plasmodium falciparum |
| Organism |
Plasmodium falciparum |
| Experiment type |
Expression profiling by array
|
| Summary |
Transcription time course of Plasmodium falciparum parasite asexual blood stage progression in the presence of antimalarial drug CID5750730 (Compound C)
|
| |
|
| Overall design |
Two-condition experiment, drug treated vs. DMSO vehicle control. Time points: 7 time points per condition. Biological replicates: 1 per condition
|
| |
|
| Contributor(s) |
Timothy R, De Silva KE, Crowley V, Shaw-Saliba K, Dube N, Josling G, Pasaje AC, Kouskoumvekaki I, Panagiotou G, Niles CJ, Jacobs-Lorena M, Okafor DC, Gamo F, Llinás M |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
May 12, 2022 |
| Last update date |
May 17, 2022 |
| Contact name |
Timothy J Russell |
| E-mail(s) |
tjr30@psu.edu
|
| Phone |
17742693971
|
| Organization name |
Pennsylvania State University
|
| Street address |
W122 Millennium Science Complex
|
| City |
STATE COLLEGE |
| State/province |
PA |
| ZIP/Postal code |
16802 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL15130 |
Agilent-037237 P.falciparum_Pf3D7v7.1_Transcriptome_apimito |
|
| Samples (14)
|
| GSM6134907 |
Compound C treated parasites 6 hpi time point |
| GSM6134908 |
Compound C treated parasites 12 hpi time point |
| GSM6134909 |
Compound C treated parasites 18 hpi time point |
| GSM6134910 |
Compound C treated parasites 24 hpi time point |
| GSM6134911 |
Compound C treated parasites 30 hpi time point |
| GSM6134912 |
Compound C treated parasites 42 hpi time point |
| GSM6134913 |
Compound C treated parasites 48 hpi time point |
| GSM6134914 |
DMSO vehicle control parasites 6 hpi time point |
| GSM6134915 |
DMSO vehicle control parasites 12 hpi time point |
| GSM6134916 |
DMSO vehicle control parasites 18 hpi time point |
| GSM6134917 |
DMSO vehicle control parasites 24 hpi time point |
| GSM6134918 |
DMSO vehicle control parasites 30 hpi time point |
| GSM6134919 |
DMSO vehicle control parasites 42 hpi time point |
| GSM6134920 |
DMSO vehicle control parasites 48 hpi time point |
|
| Relations |
| BioProject |
PRJNA837583 |
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