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Series GSE202297 Query DataSets for GSE202297
Status Public on Jun 27, 2022
Title Identification of a shared disease-associated oligodendrocyte signature among multiple CNS pathologies
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary The role of oligodendrocytes in Alzheimer’s disease (AD) has never been fully elucidated. To dissect their possible contribution to the disease we perform single-cell RNA-sequencing (scRNA-seq) on the brains of healthy and 5XFaD (genetic model of AD) at different ages.
 
Overall design We performed massively parallel single-cell RNA sequencing (MARS-seq2.0) on non-immune cells (CD45-) or specifically on oligodendrocytes (GalC+) from brains of WT and 5XFaD mice.
Web link https://doi.org/10.1038/s41593-022-01104-7
 
Contributor(s) Kenigsbuch M, Bost P
Citation(s) 35760863
Submission date May 05, 2022
Last update date Sep 28, 2022
Contact name Ido Amit
E-mail(s) ido.amit@weizmann.ac.il
Phone 972-8-9343338
Organization name Weizmann Institute of Science
Department Immunology
Street address 234 Herzl st.
City Rehovot
ZIP/Postal code 760001
Country Israel
 
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (95)
GSM6108055 AB6440
GSM6108056 AB6441
GSM6108057 AB6442
Relations
BioProject PRJNA835412

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE202297_RAW.tar 56.4 Mb (http)(custom) TAR (of TXT)
GSE202297_metadata_q.txt.gz 407.2 Kb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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