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| Status |
Public on Oct 18, 2022 |
| Title |
Assessing Cellular and Transcriptional diversity of IIeal Mucosa amongst Treatment Naïve and Treated Crohn’s disease |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Crohn’s disease (CD) is a chronic inflammatory disease of the gastrointestinal tract. We used single cell RNA sequencing (scRNAseq) to define the cellular and transcriptional activity of the mucosa at different stages of disease progression in CD.
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| Overall design |
Terminal ileal mucosal derived single cells was processed and analyzed using scRNAseq
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| Contributor(s) |
Chowdary MS, Kolachala V, Venkateswaran S, Dodd AF, Ranjit Singh P, Duke G, Hong Y, Sun Y, Xu C, Mo A, Yang J, Kosters A, Matthews J, Ghosn E |
| Citation(s) |
36206201 |
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| Submission date |
May 02, 2022 |
| Last update date |
Oct 19, 2022 |
| Contact name |
Suresh Venkateswaran |
| E-mail(s) |
svenk30@emory.edu
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| Organization name |
Emory University
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| Department |
Pediatrics
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| Street address |
1760 Haygood Drive, HSRB, Room No: E-250
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| City |
Atlanta |
| State/province |
Georgia |
| ZIP/Postal code |
30322 |
| Country |
USA |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (27)
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| Relations |
| BioProject |
PRJNA834098 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE202052_RAW.tar |
458.4 Mb |
(http)(custom) |
TAR (of MTX, TSV) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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