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| Status |
Public on Dec 28, 2022 |
| Title |
Mesenchymal EZH2 maintains uterine adenogenic homeostasis |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To determine the mesenchymal function of EZH2 in the mouse uterus, we generated Ezh2 cKO mice using anti-Mullerian hormone type 2 (Amhr2)-Cre that is expressed in the mesenchymal and not epithelial compartment of the uterus
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| Overall design |
We performed RNA-sequencing in the uteri of Ezh2 cKO mice and controls at the age of postnatal day 10:
Ctrl, PD10, 1 = HISAT2.on.data.18.and.data.17
Ctrl, PD10, 2 = HISAT2.on.data.22.and.data.21
Ctrl, PD10, 3 = HISAT2.on.data.26.and.data.25
Ctrl, PD10, 4 = HISAT2.on.data.30.and.data.29
cKO, PD10, 1 = HISAT2.on.data.34.and.data.33
cKO, PD10, 2 = HISAT2.on.data.38.and.data.37
cKO, PD10, 3 = HISAT2.on.data.42.and.data.41
cKO, PD10, 4 = HISAT2.on.data.46.and.data.45
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| Contributor(s) |
Ni N, Fang X, Li Q |
| Citation(s) |
36555314 |
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| Submission date |
May 01, 2022 |
| Last update date |
Dec 29, 2022 |
| Contact name |
Qinglei Li |
| E-mail(s) |
qli@cvm.tamu.edu
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| Organization name |
Texas A&M University
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| Street address |
400 Bizzell St
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| City |
College station |
| ZIP/Postal code |
77840 |
| Country |
USA |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (8)
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| GSM6085297 |
Ctrl, PD10, 4 |
| GSM6085298 |
cKO, PD10, 1 |
| GSM6085299 |
cKO, PD10, 2 |
| GSM6085300 |
cKO, PD10, 3 |
| GSM6085301 |
cKO, PD10, 4 |
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| Relations |
| BioProject |
PRJNA833877 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE201973_RAW.tar |
970.0 Kb |
(http)(custom) |
TAR (of TXT) |
| GSE201973_edgeR_cKO-Ctrl.tsv.gz |
1.1 Mb |
(ftp)(http) |
TSV |
| GSE201973_edgeR_normcounts.tsv.gz |
1.4 Mb |
(ftp)(http) |
TSV |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
| Processed data are available on Series record |
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