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| Status |
Public on Apr 25, 2022 |
| Title |
Tumor-associated and control mammary adipose tissue in lean and high fat diet-induced obese mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To investigate the crosstalk between a growing breast cancer tumor and adjacent adipose tissue, we set up an breast cancer mouse model and compared the gene expression between control and tumor-associated adipose tissue.
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| Overall design |
Female mice, fed either regular chow or high fat diet for 16 weeks, were injected with E0771 cancer cells resuspended in PBS mixed with Matrigel into their left inguinal/mammary fat pad (tumor-associated inguinal adipose tissue) while their right inguinal fat pad (control inguinal adipose tissue) received PBS-Matrigel solution alone. Tumor-associated and control IWAT were collected two weeks after cancer cell injections.
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| Citation(s) |
35720277 |
| Submission date |
Apr 22, 2022 |
| Last update date |
Jun 21, 2022 |
| Contact name |
Ingrid Wernstedt Asterholm |
| E-mail(s) |
IWA@neuro.gu.se
|
| Organization name |
University of Gothenburg
|
| Street address |
Box 432
|
| City |
Gothenburg |
| ZIP/Postal code |
40530 |
| Country |
Sweden |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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| Samples (22)
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| Relations |
| BioProject |
PRJNA830859 |
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