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Series GSE200276 Query DataSets for GSE200276
Status Public on Nov 23, 2022
Title A blood-brain barrier transport vehicle improves brain biodistribution of a TREM2 antibody and enhances microglial metabolism via receptor clustering
Organisms Homo sapiens; Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary This SuperSeries is composed of the SubSeries listed below.
 
Overall design Refer to individual Series
 
Citation(s) 36635496
Submission date Apr 06, 2022
Last update date Feb 22, 2023
Contact name Thomas Sandmann
E-mail(s) genomics@dnli.com, sandmann@dnli.com
Organization name Denali Therapeutics
Street address 161 Oyster Point Blvd
City South San Francisco
State/province California
ZIP/Postal code 94080
Country USA
 
Platforms (3)
GPL19057 Illumina NextSeq 500 (Mus musculus)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (101)
GSM5962062 microglia, Vehicle, day1 (DRN-22615)
GSM5962063 microglia, ATV:DNP02_10mpk, day1 (DRN-22616)
GSM5962064 microglia, DNL919_10mpk, day1 (DRN-22620)
This SuperSeries is composed of the following SubSeries:
GSE198987 Longitudinal analysis of DNL919 on microglia transcriptomics in the TB36 mouse model
GSE199154 Effects of ATV:TREM2 and pro-inflammatory stimuli on transcriptome of WT iPSC-derived microglia
GSE200275 Longitudinal scRNA-seq analysis of primary microglia from mice treated with ATV:4D9 and controls
Relations
BioProject PRJNA823923

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE200276_RAW.tar 968.2 Mb (http)(custom) TAR (of H5)
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