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| Status |
Public on Jan 06, 2024 |
| Title |
Circulating isomiRs May Be Superior Biomarkers Compared to Their Corresponding Canonical miRNAs: A Pilot Biomarker Study of Using isomiR-ome to Detect Coronary Calcium-Based Cardiovascular Risk in Patients with NAFLD |
| Organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by high throughput sequencing
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| Summary |
Cardiovascular (CV) disease is the leading cause of morbidity and mortality in patients with non-alcoholic fatty liver disease (NAFLD). Yet clinically, distinguishing between NAFLD patients with average CV risk from those at elevated risk is not easily achieved by traditional CV risk factors and clinically-based scoring systems. Here we hypothesize that in-depth analysis of circulating miRNAs can identify strong putative biomarkers for the degree of CV risk among patients with NAFLD
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| Overall design |
Plasma miRNAs of 12 NAFLD patients were sequenced by next-generation sequencing (NGS).
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| Contributor(s) |
Makarenkov N, Yoel U, Haim Y, Bhandarkar NS, Shalev A, Shelef I, Liberty IF, Arie G, Yardeni D, Rudich A, Etzion O, Veksler-Lublinsky I |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Mar 28, 2022 |
| Last update date |
Jan 06, 2024 |
| Contact name |
Nataly Makarenkov |
| E-mail(s) |
nataly@post.bgu.ac.il
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| Organization name |
Ben Gurion University
|
| Street address |
David Ben Gurion Blvd 1
|
| City |
Be'er Sheva |
| State/province |
N/A |
| ZIP/Postal code |
84105 |
| Country |
Israel |
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| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
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| Samples (13)
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| Relations |
| BioProject |
PRJNA820636 |
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