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Series GSE19836 Query DataSets for GSE19836
Status Public on Dec 06, 2010
Title A mouse Embryonic Stem Cell Bank for inducible overexpression of human chromosome 21 genes
Organism Mus musculus
Experiment type Expression profiling by array
Summary The HSA21-mES Cell Bank includes, in triplicate clones, thirty-two murine orthologs of HSA21 genes, which can be overexpressed in an inducible manner using the Tet-off system integrated in the Rosa26 locus.
The following subset of twenty clones were characterized by microarray analysis: Bach1, Erg, Ets2, Gabpa, ZFP295, Nrip1, Olig1, Olig2, Pknox1, 1810007M14Rik, Runx1, Aire, Sim2, Dscr1, DYRK1A, SNF1LK, Ripk4 , Hunk, Pdxk, Pfkl.
 
Overall design Each triplicate clone was transcriptionally profiled by microarray analysis using Affymetrix Mouse 430_2 arrays before and after induction (Affymetrix 430A_2 in case of Runx1), yielding six arrays for each overexpression experiment.
 
Contributor(s) De Cegli R, Romito A, Iacobacci S, Mao L, Lauria M, Fedele AO, Klose J, Borel C, Descombes P, Antonarakis SE, di Bernardo D, Banfi S, Ballabio A, Cobellis G
Citation(s) 20569505, 23180766
Submission date Jan 11, 2010
Last update date Feb 11, 2019
Contact name Mario Lauria
E-mail lauria@tigem.it
Phone +39 081 6132 339
Organization name TIGEM
Street address via P. Castellino 111
City Napoli
ZIP/Postal code 80131
Country Italy
 
Platforms (2)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
GPL8321 [Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array
Samples (120)
GSM495453 Aire ES clone at T0, biological rep1
GSM495454 Aire ES clone at T0, biological rep2
GSM495455 Aire ES clone at T0, biological rep3
Relations
BioProject PRJNA122055

Download family Format
SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE19836_RAW.tar 415.0 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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