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| Status |
Public on Jan 25, 2024 |
| Title |
Dyrk1a dosage effects on the transcriptome of embryonic hearts from the Dp1Tyb mouse model of Down syndrome using scRNAseq |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We performed single cell RNAseq on whole hearts from E13.5 Dp1Tyb embryos and from wild-type littermates, as well as hearts from E13.5 Dp1TybDyrk1a+/+/- embryos and wild-type littermates. We identified 14 clusters which were assigned to individual cell types based on expression of marker genes.
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| Overall design |
Single cell RNAseq analysis of 1 E13.5 Dp1Tyb heart, 3 Dp1TybDyrk1a+/+/- embryonic hearts and 3 wild-type embryonic hearts.
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| Contributor(s) |
Lana-Elola E, Llorian M, Tybulewicz V |
| Citation(s) |
38266108 |
| |
| Submission date |
Feb 09, 2022 |
| Last update date |
Apr 25, 2024 |
| Contact name |
Victor Tybulewicz |
| E-mail(s) |
Victor.T@crick.ac.uk
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| Organization name |
Francis Crick Institute
|
| Street address |
1 Midland Road
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| City |
London |
| ZIP/Postal code |
NW1 1AT |
| Country |
United Kingdom |
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| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
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| Samples (5)
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| This SubSeries is part of SuperSeries: |
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| Relations |
| BioProject |
PRJNA804912 |
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