|
| Status |
Public on Apr 26, 2024 |
| Title |
Reducing cholesteol in macrophages alters epigemone |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Cholesterol reduction in macrophages by methyl-beta-cyclodextran (MCD) alters gene expression and genomic configuration in a cholesterol specific fashion.
|
| |
|
| Overall design |
ATAC-seq was performed on RAW macrophages, treated with MCD (5 mM, 1 hour) or without. Two replicates were performed for untreated control (ctl); two replicastes for MCD treated cells MCD).
|
| |
|
| Contributor(s) |
Salloum Z, Nakka K, Zha X |
| Citation(s) |
38602170 |
| |
| Submission date |
Feb 05, 2022 |
| Last update date |
Jun 28, 2024 |
| Contact name |
Jeffrey Dilworth |
| E-mail(s) |
fdilworth@wisc.edu
|
| Phone |
6082653758
|
| Organization name |
University of Wisconsin
|
| Street address |
1111 Highland Ave
|
| City |
Madison |
| State/province |
Wisconsin |
| ZIP/Postal code |
53705 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA803744 |
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