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| Status |
Public on Mar 03, 2023 |
| Title |
Gene expression in lungs from SARS-CoV-2 mice treated with biguanides [RNAseq_murine] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Transcriptome of lung cells from mice infected with SARS-Cov-2 and treated with biguaniddes
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| Overall design |
Eight week-old male K18-human ACE2 expressing C57BL/6 mice were intranasally infected with 50 µl of DMEM containing 5x102 TCID50 of hCoV-19_IPL_France strain of SARS-CoV-2 (NCBI MW575140). LCC-12 was inoculated intranasally (0.5 mg/ml, 50 µL) 6 h post-infection, and once a day until day 2. Mice were sacrificed at day 4 post-infection.
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| Contributor(s) |
SOLIER S, MULLER S, CANEQUE T, VERSINI A, GUILLEMOT D, GESTRAUD P, TROTTEIN F, SERVANT N, WATSON S, RODRIGUEZ R |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jan 30, 2022 |
| Last update date |
Mar 03, 2023 |
| Contact name |
Nicolas Servant |
| E-mail(s) |
Nicolas.Servant@curie.fr
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| Organization name |
Institut Curie
|
| Street address |
26 rue d'ulm
|
| City |
Paris Cedex 05 |
| ZIP/Postal code |
75248 |
| Country |
France |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (19)
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| This SubSeries is part of SuperSeries: |
| GSE160864 |
Discovery of a druggable copper-signaling pathway that drives inflammation |
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| Relations |
| BioProject |
PRJNA802015 |
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