|
| Status |
Public on Jun 16, 2022 |
| Title |
Thymic epithelial cells co-opt lineage-defining transcription factors to eliminate autoreactive T cells [scATAC-seq] |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We profiled medullary thymic epithelial cells from AireWT vs AireKO mice by scATAC-seq to investigate mechanisms of T-cell tolerance.
|
| |
|
| Overall design |
scATAC-seq of mTEC
|
| |
|
| Contributor(s) |
Michelson DA, Mathis D, Benoist C |
| Citation(s) |
35714609 |
| |
| Submission date |
Jan 23, 2022 |
| Last update date |
Aug 30, 2022 |
| Contact name |
CBDM Lab |
| E-mail(s) |
cbdm@hms.harvard.edu
|
| Phone |
617-432-7747
|
| Organization name |
Harvard Medical School
|
| Department |
Microbiology and Immunobiology
|
| Lab |
CBDM
|
| Street address |
77 Avenue Louis Pasteur
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02215 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (4)
|
|
| This SubSeries is part of SuperSeries: |
| GSE194253 |
Thymic epithelial cells co-opt lineage-defining transcription factors to eliminate autoreactive T cells |
|
| Relations |
| BioProject |
PRJNA799773 |
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